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Myeloid sarcoma (MS) is a rare entity, and FDG PET/CT is a useful tool for staging at diagnosis and response assessment. We present a case of a 72-year-old woman diagnosed with multifocal extramedullary MS, using FDG PET/CT to guide palliative radiotherapy to 13 sites of disease over 2 separate relapses with complete and durable local responses and minimal toxicity. This case represents the largest reported burden of disease in MS successfully treated with FDG PET/CT-guided radiotherapy.

Four consecutive patients presented with extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the conjunctiva. After the initial resection, long-term follow-up without additional therapy showed the clinical relapse. Fluorodeoxyglucose positron emission tomography fused with computed tomography (PET/CT) showed abnormal uptake in the conjunctival relapsed lesions, which were, on reresection, again proven as MALT lymphoma. Small and thin lesions of MALT lymphoma in the conjunctiva can be detected by fluorodeoxyglucose PET/CT. The resolution of PET/CT, delineated in this study, could be applied to the other areas of the body to achieve more accurate staging of lymphoma.

A 75-year-old man, with no significant symptoms, was referred after the incidental finding of a left hilar pulmonary mass of 30 × 30 × 50 mm on a chest CT. F-18 fluorodeoxyglucose (FDG) PET/CT demonstrated a heterogeneous, moderate radiotracer uptake in the mass (SUV 3.5 g/mL). Bronchoscopy revealed a discrete extrinsic compression of the superior bronchus without endobronchial lesion. Endobronchial fine-needle biopsies could not deliver a final diagnosis. The patient underwent upper lobectomy by thoracotomy. Histopathology revealed a benign intrapulmonary schwannoma. Although rare, intermediate FDG uptake in the settings of a pulmonary mass should include schwannoma in the differential diagnosis.

A 62-year-old man with nonsmall cell lung cancer presented for a staging F-18 fluorodeoxyglucose (FDG) positron emission tomography and computed tomography. Preimaging assessment determined that the patient had a 2-week history of persistent hiccups. The hiccups were unmanageable and persisted throughout the examination from FDG injection to imaging. Persistent hiccups can be seen in patients with advanced cancer. Characteristic findings on FDG positron emission tomography and computed tomographyare presented here.

Granulocytic sarcoma (GS) is a rare disease corresponding to extramedullary tumor mostly associated with acute myelogenous leukemia. Despite the aggressiveness of leukemic cells, F-18-FDG PET is not recommended for leukemia but it may have relevance for these tumors with solid and malignant

A 55-year-old man with a small lung cancer in the right upper lobe hidden by progressive massive fibrosis (PMF) in silicosis is presented. F-18 fluorodeoxyglucose (FDG) PET/CT clearly demonstrated a small right upper lobar lung cancer, which was not definite on chest radiograph and chest CT