1. Efficacy of amlodipine in pediatric bone marrow transplant patients
- Author
-
Khattak, Sohail, Rogan, John W., Saunders, E. Fred, Theis, Jochen G.W., Arbus, Gerald S., and Koren, Gideon
- Subjects
Amlodipine -- Evaluation ,Hypertension -- Drug therapy ,Organ transplant recipients -- Care and treatment ,Bone marrow -- Transplantation ,Health - Abstract
The calcium channel blocker amlodipine may lower blood pressure in children who have received a bone marrow transplant. Organ transplant recipients must take immunosuppressive drugs to prevent graft rejection, but these drugs can often raise blood pressure. Amlodipine successfully lowered blood pressure in 15 children who had received a bone marrow transplant. Two children developed swollen ankles and had to stop taking the drug. Amlodipine is water-soluble and can be administered in a liquid form just once a day.
- Published
- 1998