1. Mean velocity and peak systolic velocity can help determine ischaemic and non-ischaemic priapism
- Author
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Suks Minhas, Navin Ramachandran, Miles Walkden, C. von Stempel, Clare Allen, A. Freeman, David Ralph, Alex Kirkham, Evangelos Zacharakis, and Asif Muneer
- Subjects
Male ,medicine.medical_specialty ,Systole ,Priapism ,030232 urology & nephrology ,Diastole ,urologic and male genital diseases ,03 medical and health sciences ,0302 clinical medicine ,Refractory ,Ischemia ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Retrospective Studies ,030219 obstetrics & reproductive medicine ,business.industry ,Penile implant ,Ultrasonography, Doppler ,Retrospective cohort study ,General Medicine ,medicine.disease ,Anesthesia ,Cohort ,Cardiology ,business ,Perfusion ,Blood Flow Velocity ,Penis - Abstract
To determine the threshold waveform characteristics at Doppler ultrasound (DUS) to differentiate between ischaemic and non-ischaemic priapism.Fifty-two patients were categorised into "ischaemic" and "non-ischaemic" types based on clinical and blood-gas findings: 10 patients with non-ischaemic priapism; 20 with ischaemic priapism before surgical shunt placement and 22 with ischaemic priapism after surgical shunt placement. DUS traces were analysed: peak systolic velocity (PSV) and mean velocity (MV) were calculated. Histological samples were obtained at the time of surgery. Three clinical outcome groups were defined: (1) normal, (2) regular use of pharmacostimulation, and (3) refractory dysfunction/penile implant.All non-ischaemic priapism cases had a PSV50 cm/s and all but one had an MV of6.5 cm/s. In pre-surgery ischaemic cases, all men had a PSV50 cm/s and MV6.5 cm/s. Two flow patterns were observed in this group: PSV25 cm/s in all men scanned before needle aspiration; and in 6/14 after needle aspiration, a high velocity/high resistance (low net inflow) pattern, with peak systolic flows22 cm/s but diastolic reversal. In post-surgery ischaemic priapism, flow parameters overlapped with the non-ischaemic group. PSV/MV did not predict clinical outcome or histology.In the present cohort, PSV50 cm/s and MV6.5 cm/s were predictive of ischaemic priapism (pre-shunt; p0.01). Patients with ischaemic priapism may show PSV22 cm/s, but have diastolic reversal and therefore low net perfusion. Post-shunt, DUS findings were extremely variable and did not predict histology or clinical outcome.
- Published
- 2017
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