1. Long-term treatment of essential arterial hypertension with nitrendipine.
- Author
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Uslenghi E, Minelli M, Bo L, Avogliero G, Amerio S, Rocci R, and Borgnino C
- Subjects
- Acebutolol therapeutic use, Blood Pressure drug effects, Drug Therapy, Combination, Female, Heart Rate drug effects, Humans, Hypertension physiopathology, Male, Middle Aged, Muzolimine therapeutic use, Nitrendipine adverse effects, Hypertension drug therapy, Nitrendipine therapeutic use
- Abstract
The efficacy and safety of long-term treatment with oral nitrendipine were evaluated in 34 patients with essential arterial hypertension. Nitrendipine alone significantly lowered systolic and diastolic blood pressure levels in 28 patients who completed the preliminary four-week dose-setting phase. Twenty-one patients completed the one-year treatment. Blood pressure control was maintained by nitrendipine alone in 11 patients. Ten patients not adequately controlled at the end of the dose-setting phase were successfully treated with nitrendipine combined with acebutolol or muzolimine. It is concluded that nitrendipine is a promising calcium antagonist for the treatment of arterial hypertension.
- Published
- 1988