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Mycosis fungoides, the most common form of cutaneous T-cell lymphoma, has a higher incidence and poorer prognosis in African-Americans. The factors that may be contributing to this disparity are presented in the context of a health disparities framework that includes discussion of patient-related factors such as race/ethnicity, socioeconomic status, and biological differences, provider-related factors such as patient-provider communication and the competing demands for providers' time, and health care system-related factors such as access to health care and workforce diversity. The changing demographics of the USA emphasize the need to understand and address health disparities in mycosis fungoides and other dermatologic diseases. The framework presented here can be used to examine disparities in other dermatologic conditions and advance health disparities research in dermatology. [ABSTRACT FROM AUTHOR]