1. β-Chitin nanofiber hydrogel as a scaffold to in situ fabricate monodispersed ultra-small silver nanoparticles.
- Author
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Song, Subin, Zhao, Yan, Yuan, Xiaoxue, and Zhang, Jinsong
- Subjects
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SILVER nanoparticles , *HYDROGELS , *X-ray photoelectron spectroscopy , *REFRACTORY materials , *FOURIER transforms - Abstract
β-chitin nanofibers (β-ChNFs) were efficiently prepared from squid pens by a combination of ball milling and ultrasonic techniques. The gellation of the β-ChNFs dispersion was achieved through a dialysis neutralization process, and hydrogels, even at 0.2% solid content, had high stiffness, as indicated by the dynamic viscoelasticity measurements. The β-ChNFs hydrogels were used as scaffolds to fabricate ultra-small silver nanoparticles (AgNPs) by in situ ultraviolet (UV) photo-reduction. High-angle annular dark-field scanning transmission energy microscopy (HAADF-STEM) analysis showed that 4 nm monodispersed AgNPs were produced in the hydrogel framework, and X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared (FT-IR) spectroscopy analysis revealed the strong interaction between AgNPs and the chitin nanofiber matrix. Furthermore, biological evaluation showed no cytotoxicity and excellent bactericidal activity of the silver nanoparticle-impregnated β-chitin nanofiber hydrogels, thus suggesting that they are promising materials to heal refractory wounds. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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