1. IRM et SRM 1H-1D in vivo à 7 T d’un modèle de régénération musculaire sur la souris
- Author
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Jean-Claude Belœil, Catherine Sébrié, and Brigitte Gillet
- Subjects
medicine.diagnostic_test ,Eosin ,Chemistry ,business.industry ,H&E stain ,Skeletal muscle ,Magnetic resonance imaging ,Histology ,General Chemistry ,Anatomy ,chemistry.chemical_compound ,medicine.anatomical_structure ,In vivo ,medicine ,Myocyte ,Nuclear medicine ,business ,Evans Blue - Abstract
In this study, skeletal muscle degeneration–regeneration, induced by notexin (a myotoxic substance) injection is studied by Magnetic Resonance Imaging (MRI) and by histological cuts (hematoxylin/eosin and Evans blue colorations). Comparison between MR images and histological cuts results (necrosis, myoblasts replication and fusion) permits MR images interpretation. From day 0 to day 13 after notexin injection, injected zone images are very different from those realized in healthy muscles. Preliminary localized 1D 1 H-MRS (Magnetic Resonance Spectroscopy) study is also reported.
- Published
- 2001
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