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Keywords: Cervical spine; intervertebral disc; collagen fibers; annulus fibrosus; FE analysis EN Cervical spine intervertebral disc collagen fibers annulus fibrosus FE analysis S129 S131 3 01/29/21 20191002 NES 191002 1. Introduction Collagen is the most prevalent protein constituting the intervertebral disc (IVD) extracellular matrix (ECM). In order to investigate the importance of the collagen network structure in the cervical IVD mechanics, we propose to perform a parametric study using an hyperelastic fiber reinforced finite element (FE) model of cervical IVD. The obtained results did not only show the importance of the collagen network structure for the IVD behavior, but also confirmed that simulating the IVD mechanics under non axial loads strongly requires the use of a fiber reinforced model. [Extracted from the article]

The article presents information on collagen fibers in soft tissues, focusing on intervertebral disc collagen networks consisting of nucleus pulposus, finite element modeling, and biphasic swelling. Topics include axial loads, collagen fibers and its impact, isotropic iron modeling, and mechanical behavior of tissues.

The article presents a study which determines the effect of large deformations on the nutrient processes when compares to the older linear model. It describes a finite deformation formulation to model the mechanical behavior of intervertebral disk (IVD) during these large deformations. Results of the research showed that linear model overestimates water waste and nutrient concentration variations within the IVD.