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A medical cyber-physical system (MCPS) integrates medical sensor devices with cyber (information) components, which creates a sensitive approach and provides security. The MCPS plays a vital role in hospitals by detecting attacks and protecting patients' medical information. Many research projects have been carried out to detect attacks on the generation of medical information in MCPS. The issues with existing algorithms are their inefficiency and time-consuming maximization of error rates. To overcome the challenges, this paper proposes detecting the attack using the fuzzy C-Means algorithm with artificial bee colony optimization (FCM-ABC). The novelty of the work is flexibility in deciding whether data points belong to actual users or attackers using the fuzzy c means degree [0,1] measuring technique of cluster formation. ABC is used in self-organizing the clusters with ABC collective intelligence. It monitors health information using sensor networks. The MCPS model interconnects the sensor devices remotely and collects the information. SVM has an accuracy rate of 76.32%, FCM has an accuracy rate of 81.34%, LSTM has an accuracy rate of 86.22%, and our proposed work, FCM-ABC, has an accuracy rate of 93.34%. [ABSTRACT FROM AUTHOR]

• Biologically inspired heuristics for target search lack modularity and modifiability. • The proposed hyper-heuristic is based on modular and adaptive swarm behavior. • Combining stigmergy, flocking and evolution outperforms bio-inspired heuristics. Target search aims to discover elements of various complexity in a physical environment, by minimizing the overall discovery time. Different swarm intelligence algorithms have been proposed in the literature, inspired by biological species. Despite the success of bio-inspired techniques (bio-heuristics), there are relevant algorithm selection and parameterization costs associated with every new type of mission and with new instances of known missions. In this paper, evolutionary optimization is proposed for achieving significant improvements of the mission performance. Although adaptive, the logic of bio-heuristics is nevertheless constrained by models of biological species. To generate more adaptable logics, a novel design approach based on hyper-heuristics is proposed, in which the differential evolution optimizes the aggregation and tuning of modular heuristics for a given application domain. A modeling and optimization testbed has been developed and publicly released. Experimental results on real-world scenarios show that the hyper-heuristics based on stigmergy and flocking significantly outperform the adaptive bio-heuristics. [Display omitted] [ABSTRACT FROM AUTHOR]