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Mobile wireless sensor networks (MWSNs) have become an area of intense research activity due to technical advances in sensors, wireless communications and networking, and signal processing. Many applications, including environment monitoring, battlefield surveillance, and urban search and rescue especially in hazardous situations, are envisaged. However, MWSNs may be vulnerable to malicious interference because of the large-scale characteristics. When a contaminated node communications with its neighbors, multiple copies of the malware are transmitted to its neighbors, which may destroy, block regular communications, or even damage the integrity of regular data packets. Modeling spatial distribution of malware propagation over time is the first step to predict the trend of malware propagation in MWSNs. We propose a novel wireless malware propagation model with the discrete time delay based on reaction–diffusion equations in mobile wireless sensor networks, and study its dynamic behaviors. By analyzing the stability and Hopf bifurcation of the equilibrium of our model, we search for the sufficient conditions, which leads to the malware propagation disappears or continues. Furthermore, we demonstrate that oscillations in this model occur through the destabilization of the stationary solution at a Hopf bifurcation point. And formulas for determining the stability of the bifurcating periodic oscillations are derived by applying the normal form method and center manifold theorem. Finally, we conduct extensive simulations on large-scale MWSNs to evaluate the proposed model. Numerical evidence shows that the spatial–temporal dynamic characteristics of malware propagation in MWSNs are closely related to the packet transmission rate, the communication rang and the mobile behavior of nodes. [ABSTRACT FROM AUTHOR]