1. Diagnosis and management of typical and atypical lung carcinoids.
- Author
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Pusceddu, Sara, Lo Russo, Giuseppe, Macerelli, Marianna, Proto, Claudia, Vitali, Milena, Signorelli, Diego, Ganzinelli, Monica, Scanagatta, Paolo, Duranti, Leonardo, Trama, Annalisa, Buzzoni, Roberto, Pelosi, Giuseppe, Pastorino, Ugo, de Braud, Filippo, and Garassino, Marina Chiara
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LUNG cancer treatment , *NEUROENDOCRINE tumors , *CARCINOID , *DISEASE incidence - Abstract
An estimated 20% to 30% of all neuroendocrine tumours originate in the bronchial tree and lungs. According to the 2015 World Health Organization categorization, these tumours are separated into four subtypes characterized by increasing biological aggressiveness: typical carcinoid, atypical carcinoid, large-cell neuroendocrine carcinoma and small-cell carcinoma. Although typical and atypical lung carcinoids account for less than 1–5% of all pulmonary malignancies, the incidence of these neoplasms has risen significantly in recent decades. Surgery is the treatment of choice for loco-regional disease but for advanced lung carcinoids there is no recognized standard of care and successful management requires a multidisciplinary approach. The aim of this review is to provide a useful guide for the clinical management of lung carcinoids. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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