1. Positron emission tomography with computed tomography imaging (PET/CT) for the radiotherapy planning definition of the biological target volume: PART 2
- Author
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Pierpaolo Alongi, Laura Evangelista, Lorenza Marino, Salvatore Annunziata, Paolo Borghetti, Maria Elisabetta Ricci, Agostino Chiaravalloti, Michele Fiore, Isacco Desideri, Elisa Ciurlia, Carmelo Tuscano, Federico Caobelli, Paola Mapelli, Alba Fiorentino, Riccardo Laudicella, Valentina Lancellotta, and Natale Quartuccio
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0301 basic medicine ,medicine.medical_specialty ,PET/CT ,Colorectal cancer ,Image Processing ,medicine.medical_treatment ,Radiotherapy Planning ,Rectum ,Imaging ,03 medical and health sciences ,Prostate cancer ,Computer-Assisted ,0302 clinical medicine ,Neoplasms ,Positron Emission Tomography Computed Tomography ,Pancreatic cancer ,Image Processing, Computer-Assisted ,medicine ,Humans ,Anal cancer ,Radiotherapy ,Target volume ,Radiotherapy Planning, Computer-Assisted ,Radiotherapy, Image-Guided ,PET-CT ,medicine.diagnostic_test ,business.industry ,Hematology ,medicine.disease ,Radiation therapy ,030104 developmental biology ,medicine.anatomical_structure ,Image-Guided ,Oncology ,Positron emission tomography ,030220 oncology & carcinogenesis ,Radiology ,business - Abstract
Aim Positron Emission Tomography with Computed Tomography (PET/CT) has been proven to be useful in the definition of Radiotherapy (RT) target volume. In this regard, the present expert review summarizes existing data for pancreas, prostate, gynecological and rectum/anal cancer. Methods A comprehensive search of published original article was made, based on SCOPUS and PubMed database, selecting the paper that evaluated the role of PET/CT in the definition of RT volume. Results FDG-PET has an important and promising role for pancreatic cancer. Choline PET/CT could be useful for identifying high-risk volumes for prostate cancer; while PSMA PET/CT is still under evaluation. FDG PET/CT in gynecological cancers has been shown to impact external-beam RT planning. The role of FDG-PET for Gross Tumor volume identification is crucial, representing a useful and powerful tool for anal and rectal cancer. Conclusion Taken together, molecular and functional imaging approaches offer a major step to individualize radiotherapeutic approach.
- Published
- 2019
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