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Start Over Author "Sarah E. Wilkins" Journal current opinion in structural biology
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1. Structure-function relationships of human JmjC oxygenases-demethylases versus hydroxylases

Author

Suzana, Markolovic, Thomas M, Leissing, Rasheduzzaman, Chowdhury, Sarah E, Wilkins, Xin, Lu, and Christopher J, Schofield

Subjects
Jumonji Domain-Containing Histone Demethylases, Structure-Activity Relationship, Biocatalysis, Animals, Humans, Protein Multimerization, Mixed Function Oxygenases
Abstract

The Jumonji-C (JmjC) subfamily of 2-oxoglutarate (2OG)-dependent oxygenases are of biomedical interest because of their roles in the regulation of gene expression and protein biosynthesis. Human JmjC 2OG oxygenases catalyze oxidative modifications to give either chemically stable alcohol products, or in the case of N

Published
2016

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