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Based on the complex population study of 2083 children aged from 12 to 17 years old it was established that living in Chelyabinsk regions with different cumulative levels of antropogenic air pollution affect physical development of adolescents. It was shown that air pollution increases the risk of disharmonic physical development in girls which is represented by the decrease of the thoracic circumference, which simultaneously with their growth appears as gracilization of body constitution. Changes in adolescents height can be various . From one hand, xenobiotics of the atmosphere can have stimulative effects, which are more marked with low-dosage exposure. From the other hand, there is a tendency to increase in percentage of children with short height in the conditions if the increased level of antropogenic burden.