1. High benzoic acid production in a grape-based Ayurvedic medicinal wine (asava).
- Author
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Tomy, Muringayil Joseph, Sharanya, Chelankara Suresh, Sabu, Abdulhameed, and Haridas, Madhathil Kovilakathu
- Subjects
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BENZOIC acid , *LIPOXYGENASES , *METABOLITES , *ENZYME inhibitors , *INFLAMMATION - Abstract
Fermentative production of benzoic acid is seldom reported and the present report serendipitously expressed it, though in small quantity (~30 mg/l). Lipoxygenases (LOXs) catalyse the stereo-specific insertion of molecular oxygen into arachidonic acid, leading to hydroxy derivatives as end products. Serendipitously found LOX inhibitor was benzoic acid, produced in Ayurvedic-fermented medicated wine, pippalyasava. The present study reports the significance of the polyphenol derivatives in a traditional Ayurvedic therapeutic preparation where LOX inhibition might have a role, besides its importance in fermented benzoic acid production. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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