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1. Linkage mapping detects two secondary microdeletions in cell hybrid HHW1064, used to isolate DNA probes from within 5q11.2-->q13.3.

Author

Bernard LE, McPherson JD, Wasmuth JJ, Kreklywich CN, Brzustowicz LM, and Wood S

Subjects
Chromosome Mapping, Female, Genetic Linkage, Genetic Markers, Humans, Hybrid Cells, Karyotyping, Male, Polymerase Chain Reaction, Chromosomes, Human, Pair 5, Gene Deletion
Abstract

The somatic cell hybrid HHW1064 contains a single human chromosome 5 with an interstitial deletion for 5q11.2-->q13.3. Twenty human clones were isolated by Alu-PCR differential hybridization. Mapping these clones indicates that HHW1064 contains two additional secondary microdeletions.

Published
1993
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