1. Management of cytologic material, preanalytic procedures and biobanking in lymph node cytopathology
- Author
-
Beata Bode-Lesniewska, Immacolata Cozzolino, Pio Zeppa, and Helena Barroca
- Subjects
medicine.medical_specialty ,Histology ,Sample (material) ,Cytodiagnosis ,030209 endocrinology & metabolism ,Pathology and Forensic Medicine ,Specimen Handling ,Cytologic material ,03 medical and health sciences ,biobanking ,0302 clinical medicine ,cytopathology ,Neoplasms ,medicine ,Humans ,Medical physics ,Lymph node ,Cell block ,In Situ Hybridization, Fluorescence ,Biological Specimen Banks ,business.industry ,General Medicine ,lymph node ,Flow Cytometry ,Biobank ,medicine.anatomical_structure ,Cytopathology ,030220 oncology & carcinogenesis ,Liquid-based cytology ,biobanking, lymph node, cytopathology ,Lymph Nodes ,business - Abstract
The range of pathologies that lymph node (LN) fine needle cytology (FNC) may encounter is extremely wide and ancillary techniques, in addition to traditional smears, are generally required to reach reliable cytologic diagnoses. Storing part of the cytologic material may be useful or necessary for molecular testing. The main difficulties concern the generally small size of the sample and the different methods of acquisition of LN-FNC. Therefore, the preanalytic phase is extremely important for LN-FNC. This article outlines the management of LN-FNC material, vials, technical devices (e.g.: additional smears, cytospin slides, LBC slides, cards, resins, etc.) and main ancillary techniques to assess their optimal application, taking into account the different diagnostic needs and cell storage.
- Published
- 2017