1. A New Scoring Method of the Mini-Mental Status Examination to Screen for Dementia.
- Author
-
Choe, Jin Yeong, Han, Ji Won, Kim, Tae Hui, Kim, Jeong Lan, Moon, Seok Woo, Park, Joon Hyuk, Kim, Shin Gyeom, Kim, Bong-Jo, Kwak, Kyung-Phil, Ryu, Seung-Ho, Yoon, Jong Chul, Lee, Dong Young, Lee, Dong Woo, Lee, Seok Bum, Lee, Jung Jae, Jhoo, Jin Hyeong, and Kim, Ki Woong
- Subjects
DIAGNOSIS of dementia ,REFERENCE values ,STATISTICAL correlation ,PEARSON correlation (Statistics) ,RESEARCH funding ,SECONDARY analysis ,T-test (Statistics) ,DATA analysis ,RECEIVER operating characteristic curves ,RESEARCH methodology evaluation ,DESCRIPTIVE statistics ,CHI-squared test ,LONGITUDINAL method ,PSYCHOMETRICS ,NEUROPSYCHOLOGICAL tests ,STATISTICAL reliability ,STATISTICS ,RESEARCH ,ANALYSIS of variance ,MEDICAL screening ,CONFIDENCE intervals ,SENSITIVITY & specificity (Statistics) ,PREDICTIVE validity - Abstract
Background: Although the Mini-Mental Status Examination (MMSE) is the most widely used screening instrument for dementia, it has several limitations. Methods: We developed and validated a new scoring method of the MMSE, namely the short form of the MMSE (MMSE-S). Results: The MMSE-S was more robust to demographic influences than the MMSE. The influence of education, in particular, was smaller in the MMSE-S compared to the MMSE (p < 0.01). The diagnostic accuracy of the MMSE-S for very mild to mild dementia was also better than that of the original MMSE (p < 0.0001). Its specificity, in particular, was higher than that of the original MMSE. In Korea, we could improve the post-test probability for dementia from 46.88 to 64.76% by employing the MMSE-S instead of the MMSE. We also provided optimal cut-off scores for dementia stratified by age, education, and gender, which may further improve the diagnostic accuracy of the MMSE-S for dementia. Conclusion: Due to its good accuracy and brevity, the MMSE-S may contribute to enhancing the cost-effectiveness of and accessibility to dementia screening as well as early diagnosis and treatment of dementia, particularly in low- and middle-income countries. © 2014 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF