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Start Over Author "Leiv Sandvik" Journal dementia and geriatric cognitive disorders
7 results on '"Leiv Sandvik"'

1. Contents Vol. 27, 2009

Author

Carlo Caltagirone, Ladson Hinton, M. Quintana, Brynjar Fure, Björn Hultberg, S. de Sola, Walter Valfrè, Elisa Rubino, Ronald E. Gangnon, Massimo Musicco, Mary N. Haan, Giuseppina D’Amico, Giuseppe Gambina, Jane E. Mahoney, Leiv Sandvik, Laurel A. Beckett, Douglas Hinerfeld, Serena Mosti, Jørgen Wagle, Peter St George-Hyslop, Lorenzo Pinessi, Brynhild Stensrød, G. Sánchez-Benavides, Patrizia Ferrero, Yan Li, Salvatore Gallone, Carey E. Gleason, Richard J. Caselli, Giuseppe Moretto, Yolanda Hagar, J. Peña-Casanova, Denisa Baci, Giovanna Vaula, L Ulizzi, Stephen P. Baker, Ekaterina Rogaeva, Renato Scacchi, Giorgetta Cappa, Karin Nilsson, Barbara L. Fischer, Lars Gustafson, Keith A. Josephs, Ping-Yiu Yik, Eugenia Rota, Knut Engedal, R.M. Manero, Bradley F. Boeve, Barbara A. Evans, Leung-Wing Chu, S. Quiñones-Úbeda, Rosa Maria Corbo, Torgeir Bruun Wyller, Luca Cravello, Zhong Li, Preben Bo Mortensen, Concetta Di Lorenzo, Innocenzo Rainero, Alexander Kurz, Lars Vedel Kessing, James E. Evans, Katie Palmer, Majaz Moonis, Kevin J. Kane, Thien Kieu Thi Phung, Kjell Flekkøy, Kristin L. Eiklid, Brendan J. Kelley, Hector M. González, Giovanna Salamone, Joan M. Swearer, You-Qiang Song, Horst Bickel, Nancy West, Gunhild Waldemar, Daniel A. Pollen, P Fenoglio, Federica Lupo, Lasse Farner, Birgitte Bo Andersen, and Dan M Mungas

Subjects
Psychiatry and Mental health, Cognitive Neuroscience, Geriatrics and Gerontology
Published
2009

2. Association between ApoE ε4 and Cognitive Impairment after Stroke

Author

Jørgen Wagle, Brynhild Stensrød, Kjell Flekkøy, Kristin L. Eiklid, Torgeir Bruun Wyller, Knut Engedal, Brynjar Fure, Leiv Sandvik, and Lasse Farner

Subjects
Male, Apolipoprotein E, medicine.medical_specialty, Genotype, Cognitive Neuroscience, Apolipoprotein E4, Neuropsychological Tests, Brain Ischemia, Developmental psychology, Apolipoproteins E, Degenerative disease, Physical medicine and rehabilitation, Risk Factors, Aphasia, medicine, Humans, Dementia, Association (psychology), Cognitive impairment, Stroke, Aged, Cerebral Hemorrhage, business.industry, Cognitive disorder, Cognition, DNA, Middle Aged, medicine.disease, Psychiatry and Mental health, Logistic Models, Cardiovascular Diseases, Cerebrovascular Circulation, Female, Geriatrics and Gerontology, Cognition Disorders, business, Psychomotor Performance
Abstract

Background and Purpose: The understanding of the contribution of genetic factors to cognitive impairment after stroke is incomplete. The aim of the study was to examine whether the apolipoprotein E ε4 allele (ApoE ε4) is a risk factor for cognitive impairment in the early phase after stroke. Methods: The sample comprised 152 Norwegian stroke rehabilitation inpatients (mean age 76.8 years, SD 10.5) examined at a mean of 18.3 days (SD 13.4) after hospital admission. Post-stroke cognitive impairment was assessed with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). The following proposed risk factors were analysed: ApoE genotype, demographics (age, sex, education), pre-stroke cognitive reduction [Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)], pre-stroke vascular factors (including previous stroke), stroke characteristics (type, location), and neurological stroke-related impairment [National Institutes of Health Stroke Scale (NIHSS)]. Cognitive impairment was defined as an RBANS total index score ≤1.5 SD below the mean. Multiple logistic regression analyses were performed to find risk factors for post-stroke cognitive impairment. Results: Four variables were found to be independent risk factors for cognitive impairment after stroke: ApoE ε4 (OR = 3.7; 95% CI = 1.2–11.6), IQCODE score ≥3.44 (OR = 9.2; 95% = CI 2.3–37.2), total or partial anterior stroke syndromes (OR = 3.2; 95% CI = 1.3–8.0), and NIHSS total score >5 (OR = 7.3; 95% CI = 2.7–19.7). No association between ApoE ε4 and pre-stroke cognitive reduction (IQCODE) was found. Conclusions: The presence of one or two ApoE ε4 alleles may be a significant independent risk factor for cognitive impairment in the early phase after stroke.

Published
2009

3. Contents Vol. 24, 2007

Author

Steen G. Hasselbalch, Gunhild Waldemar, Roger Bullock, Stephen Todd, Raymond L.C. Vogels, T.K. Nilsson, Eric Salmon, Ann-Sofie Teller, Oriana Pelati, Anjan Chatterjee, Samantha Pradelli, Ming-X Tang, Kazi Elina, Enzo Grossi, Bruno Vellas, Laura Bracco, Geoffrey K. Aguirre, Peachie Moore, Carolina Piccini, J. McGuire, H. Branch Coslett, David J. Libon, S. Murphy, Michela Baccini, S.D. Rountree, Ingun Ulstein, Barbera van Harten, Miriam Caputo, Frans R.J. Verhey, Emma Reynish, Sara Ercolani, E.J. Darby, Richard Mayeux, Yaakov Stern, Pierre Jean Ousset, Lauren Massimo, W.W. Liu, Rita Savarè, David Craig, Janet A. Johnston, Sandro Sorbi, D.T.R. Coulson, Marina Boziki, Clive Holmes, S.C. Waring, W.C. Chan, Wiesje M. van der Flier, Anna Marriott, Philip Scheltens, Leiv Sandvik, V.N. Podust, Luc De Vreese, G.B. Irvine, Anthony Peter Passmore, Joseph H. Lee, E. Mariani, Philippe Robert, Paolo Caffarra, Vincent Camus, Flavio Nobili, M. Caputo, Alida A. Gouw, Aaron Rice, Anja Hviid Simonsen, Patrizia Mecocci, P. Mecocci, U. Senin, F.T. Feliziani, Peter Høgh, Nicole Schupf, Elisabeth Kapaki, Peter Paul De Deyn, Nicola Girtler, Debby Collins, Magda Tsolaki, Knut Engedal, E. J. Byrne, D.F. Vitale, Henry C. Weinstein, Luisa Vesely, Renata Cerutti, Jutta M. Schroeder-Tanka, N.-O. Hagnelius, Rachelle S. Doody, Massimo Franceschi, Pauline Aalten, Beverly Johnson, Joukje M. Oosterman, Francesca Mangialasche, Torgeir Bruun Wyller, Murray Grossman, Benedetta Nacmias, Catherine S Hurt, P.J. Lupo, R. Monastero, D. Vassilopoulos, Vincent Santana, Giovanni B. Frisoni, Federica Biancucci, Silvia Bagnoli, and Valentina Bessi

Subjects
Psychiatry and Mental health, Cognitive Neuroscience, Geriatrics and Gerontology
Published
2007

4. Early post-stroke cognition in stroke rehabilitation patients predicts functional outcome at 13 months

Author

Brynjar Fure, Jørgen Wagle, Brynhild Stensrød, Leiv Sandvik, Torgeir Bruun Wyller, Lasse Farner, Knut Engedal, and Kjell Flekkøy

Subjects
Adult, Male, medicine.medical_specialty, Activities of daily living, Cognitive Neuroscience, medicine.medical_treatment, Neuropsychological Tests, Central nervous system disease, Cognition, Sex Factors, Predictive Value of Tests, Surveys and Questionnaires, Activities of Daily Living, medicine, Dementia, Humans, Stroke, Aged, Aged, 80 and over, Rehabilitation, Cognitive disorder, Age Factors, Stroke Rehabilitation, Recovery of Function, Middle Aged, medicine.disease, Prognosis, Psychiatry and Mental health, Treatment Outcome, Socioeconomic Factors, Predictive value of tests, Physical therapy, Educational Status, Female, Geriatrics and Gerontology, Psychology, Cognition Disorders, Biomarkers, Follow-Up Studies
Abstract

Objective: To identify prognostic factors associated with functional outcome at 13 months in a sample of stroke rehabilitation patients. Specifically, we hypothesized that cognitive functioning early after stroke would predict long-term functional outcome independently of other factors. Methods: 163 stroke rehabilitation patients underwent a structured neuropsychological examination 2–3 weeks after hospital admittance, and their functional status was subsequently evaluated 13 months later with the modified Rankin Scale (mRS) as outcome measure. Three predictive models were built using linear regression analyses: a biological model (sociodemographics, apolipoprotein E genotype, prestroke vascular factors, lesion characteristics and neurological stroke-related impairment); a functional model (pre- and early post-stroke cognitive functioning, personal and instrumental activities of daily living, ADL, and depressive symptoms), and a combined model (including significant variables, with p value Results: A combined model of 4 variables best predicted long-term functional outcome with explained variance of 49%: neurological impairment (National Institute of Health Stroke Scale; β = 0.402, p < 0.001), age (β = 0.233, p = 0.001), post-stroke cognitive functioning (Repeatable Battery of Neuropsychological Status, RBANS; β = –0.248, p = 0.001) and prestroke personal ADL (Barthel Index; β = –0.217, p = 0.002). Further linear regression analyses of which RBANS indexes and subtests best predicted long-term functional outcome showed that Coding (β = –0.484, p < 0.001) and Figure Copy (β = –0.233, p = 0.002) raw scores at baseline explained 42% of the variance in mRS scores at follow-up. Conclusions: Early post-stroke cognitive functioning as measured by the RBANS is a significant and independent predictor of long-term functional post-stroke outcome.

Published
2011

5. A one-year randomized controlled psychosocial intervention study among family carers of dementia patients--effects on patients and carers

Author

Torgeir Bruun Wyller, Knut Engedal, Leiv Sandvik, and Ingun Ulstein

Subjects
Male, medicine.medical_specialty, health care facilities, manpower, and services, Cognitive Neuroscience, MEDLINE, Neuropsychological Tests, law.invention, Randomized controlled trial, Cost of Illness, law, health services administration, Intervention (counseling), medicine, Prevalence, Dementia, Humans, Psychology, Psychiatry, health care economics and organizations, Aged, Retrospective Studies, Family Health, Cognitive disorder, Retrospective cohort study, social sciences, Middle Aged, medicine.disease, Intervention studies, Psychotherapy, Psychiatry and Mental health, Caregivers, Female, Geriatrics and Gerontology, human activities, Psychosocial, Stress, Psychological
Abstract

Objective: To test the effect of a short-term psychosocial intervention programme for family carers of patients with dementia and identify characteristics of carers and patients that responded positively. Methods: The study was a multi-centre randomized controlled trial. Carers of 180 patients suffering from dementia recruited at 7 memory clinics at geriatric or psychiatric departments participated in the study. Carers of the intervention group were educated about dementia and in 6 group meetings taught how to use structured problem-solving. The control group received treatment as usual. The effect on patients was measured with the Neuropsychiatric Inventory and on carers with the Relatives’ Stress Scale (RSS). Results: The intention-to-treat efficacy analysis included 171 carer/patient dyads. The intervention did not have any effect on the primary outcome variables. The burden measured by the RSS increased in both groups; however, more carers of the control group converted from a low-burden group to a medium- or high-burden group after 4.5 months. In a subgroup analysis we found a statistically significant difference in the Neuropsychiatric Inventory score in favour of the intervention group among female patients. Conclusion: The predominately negative result of this study emphasizes the need of individually tailored interventions for carers and the use of narrow inclusion criteria when performing group-based interventions, such as the extent of burden as well as gender and kinship.

Published
2007

6. Subject Index Vol. 27, 2009

Author

Massimo Musicco, Richard J. Caselli, G. Sánchez-Benavides, Giuseppina D’Amico, Yolanda Hagar, Federica Lupo, Denisa Baci, Giuseppe Gambina, Jane E. Mahoney, M. Quintana, Joan M. Swearer, Giorgetta Cappa, Ekaterina Rogaeva, Leiv Sandvik, Laurel A. Beckett, You-Qiang Song, Birgitte Bo Andersen, Katie Palmer, Mary N. Haan, Walter Valfrè, Luca Cravello, Horst Bickel, James E. Evans, R.M. Manero, Thien Kieu Thi Phung, Nancy West, Salvatore Gallone, Rosa Maria Corbo, Lasse Farner, Majaz Moonis, Kevin J. Kane, Serena Mosti, Ping-Yiu Yik, Brynjar Fure, Barbara L. Fischer, Brendan J. Kelley, Concetta Di Lorenzo, Torgeir Bruun Wyller, Carlo Caltagirone, Ladson Hinton, Leung-Wing Chu, Björn Hultberg, Hector M. González, Lars Vedel Kessing, Zhong Li, P Fenoglio, Dan M Mungas, Carey E. Gleason, Innocenzo Rainero, Alexander Kurz, Karin Nilsson, Eugenia Rota, Jørgen Wagle, Kjell Flekkøy, Preben Bo Mortensen, S. Quiñones-Úbeda, Gunhild Waldemar, Peter St George-Hyslop, Brynhild Stensrød, Daniel A. Pollen, J. Peña-Casanova, Knut Engedal, Barbara A. Evans, Yan Li, Elisa Rubino, Kristin L. Eiklid, Lars Gustafson, Patrizia Ferrero, Bradley F. Boeve, Douglas Hinerfeld, S. de Sola, Ronald E. Gangnon, Lorenzo Pinessi, L Ulizzi, Stephen P. Baker, Keith A. Josephs, Giuseppe Moretto, Giovanna Vaula, Giovanna Salamone, and Renato Scacchi

Subjects
Psychiatry and Mental health, Index (economics), Cognitive Neuroscience, Statistics, Subject (documents), Geriatrics and Gerontology, Mathematics
Published
2009

7. Subject Index Vol. 24, 2007

Author

Miriam Caputo, Knut Engedal, D.F. Vitale, Anna Marriott, Henry C. Weinstein, Nicole Schupf, Emma Reynish, N.-O. Hagnelius, Giovanni B. Frisoni, Federica Biancucci, Oriana Pelati, David J. Libon, Beverly Johnson, Patrizia Mecocci, P. Mecocci, Sara Ercolani, W.C. Chan, Paolo Caffarra, S.D. Rountree, Jutta M. Schroeder-Tanka, E. Mariani, Philippe Robert, Geoffrey K. Aguirre, Steen G. Hasselbalch, Francesca Mangialasche, Joseph H. Lee, Murray Grossman, M. Caputo, Raymond L.C. Vogels, Benedetta Nacmias, F.T. Feliziani, Peter Høgh, Vincent Camus, Sandro Sorbi, Torgeir Bruun Wyller, Philip Scheltens, Vincent Santana, Joukje M. Oosterman, E.J. Darby, Ming-X Tang, D.T.R. Coulson, Ann-Sofie Teller, U. Senin, S.C. Waring, Kazi Elina, Janet A. Johnston, Catherine S Hurt, Wiesje M. van der Flier, Richard Mayeux, David Craig, Gunhild Waldemar, Clive Holmes, Anthony Peter Passmore, T.K. Nilsson, P.J. Lupo, Peter Paul De Deyn, Marina Boziki, Eric Salmon, Laura Bracco, G.B. Irvine, Bruno Vellas, Luc De Vreese, Magda Tsolaki, Anja Hviid Simonsen, Peachie Moore, Elisabeth Kapaki, H. Branch Coslett, Michela Baccini, Luisa Vesely, W.W. Liu, E. J. Byrne, Yaakov Stern, Nicola Girtler, S. Murphy, R. Monastero, Ingun Ulstein, Barbera van Harten, D. Vassilopoulos, V.N. Podust, Pierre Jean Ousset, Rita Savarè, Lauren Massimo, Debby Collins, Aaron Rice, Alida A. Gouw, Flavio Nobili, Stephen Todd, J. McGuire, Frans R.J. Verhey, Enzo Grossi, Carolina Piccini, Anjan Chatterjee, Samantha Pradelli, Pauline Aalten, Roger Bullock, Renata Cerutti, Rachelle S. Doody, Massimo Franceschi, Leiv Sandvik, Silvia Bagnoli, and Valentina Bessi

Subjects
Psychiatry and Mental health, Index (economics), Cognitive Neuroscience, Statistics, Subject (documents), Geriatrics and Gerontology, Mathematics
Published
2007

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