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Your search keyword '"Toffoli, L"' showing total 5 results
Start Over Author "Toffoli, L" Journal dermatologic therapy
5 results on '"Toffoli, L"'

1. An unusual presentation of genital herpes in a patient affected by lichen sclerosus et atrophicus: A case report and a combined treatment proposal

Author

Iris Zalaudek, Nicola di Meo, Roberta Vezzoni, Chiara Retrosi, Ludovica Toffoli, Roberta Giuffrida, Claudio Conforti, Conforti, C., Toffoli, L., Giuffrida, R., Retrosi, C., Vezzoni, R., Di Meo, N., and Zalaudek, I.

Subjects
Combined Modality Therapy, Humans, Skin, Herpes Genitalis, Lichen Sclerosus et Atrophicus, Herpes simplex, medicine.medical_specialty, treatment, genitals, business.industry, Patient affected, Dermatology, General Medicine, Lichen sclerosus, medicine.disease, Combined treatment, Medicine, Presentation (obstetrics), business, Genital herpes
Abstract

N/A

Published
2020
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2. Locally advanced basal cell carcinoma: Real-life data with sonidegib.

Author

Toffoli L, Conforti C, Zelin E, Vezzoni R, Agozzino M, di Meo N, and Zalaudek I

Subjects
Biphenyl Compounds, Hedgehog Proteins therapeutic use, Humans, Pyridines, Quality of Life, Antineoplastic Agents adverse effects, Carcinoma, Basal Cell pathology, Skin Neoplasms pathology
Abstract

In recent years, the category of hedgehog pathway inhibitor (HHI) has shown great results in patients with advanced basal cell carcinoma (aBCC), but few real-life data on efficacy and safety profile of sonidegib are available. We report our management of locally advanced BCCs (laBCCs) with sonidegib, also describing the favorable response of locally advanced basosquamous carcinomas (laBSCs) treated with this hedgehog signaling inhibitor. Sonidegib was generally well tolerated and it achieved high response rates, improving quality of life. Our single-center experience could be useful to better delineate long-term efficacy and tolerability profile demonstrated in the trials described in literature. Moreover, our cases provide preliminary evidence that sonidegib might be effective for laBSC., (© 2022 Wiley Periodicals LLC.)

Published
2022
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