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10 results on '"Yasushi Tomita"'

1. Characteristic Intracytoplasmic Material in a Perianal Wart That Contains Human Papillomavirus Type 56 and 16 DNA

Author

Tamio Suzuki, Ayumi Adachi, and Yasushi Tomita

Subjects
Adult, Sexually transmitted disease, Pathology, medicine.medical_specialty, Erythema, Dot blot, Dermatology, Biology, Polymerase Chain Reaction, Inclusion Bodies, Viral, Eosinophilic, medicine, Atypia, Humans, Papillomaviridae, In Situ Hybridization, Southern blot, Anus Diseases, virus diseases, Anus, medicine.disease, Blotting, Southern, medicine.anatomical_structure, Dysplasia, RNA, Viral, Female, Warts, medicine.symptom
Abstract

We report the case of a perianal wart in which human papillomavirus type 56 and 16 DNAs were detected, arising in a 29-year-old healthy Japanese female. Clinically, moist erythema and small flat pinkish papules appeared around the anus and worsened over a period of 6 months. Histopathologically, no signs of dysplasia or atypia were apparent. An area of intracytoplasmic material, which was homogeneous and eosinophilic, was contained in each epidermal cell. The wart showed HPV-56 and HPV-16 DNAs by PCR and reverse-phase dot blot hybridization. Additional Southern blot analysis showed the amount of HPV-56 DNA to be more than 10 times that of HPV-16 DNA. This is the first case, to our knowledge, of a perianal wart with intracytoplasmic material, which contains HPV DNAs causing mucous lesions.

Published
2001
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2. Giant Xanthomatous Dermatofibroma – A Case Distinguished Histologically and Immunohistochemically from Invasive Fibrohistiocytic Tumors

Author

Noriko Sato, O. Maie, Yasushi Tomita, and S. Aiba

Subjects
Pathology, medicine.medical_specialty, Skin Neoplasms, Histiocytoma, Benign Fibrous, business.industry, Skin tumor, Dermatology, Middle Aged, Immunohistochemistry, Dermatofibroma, Diagnosis, Differential, Xanthomatosis, medicine, Humans, Female, Differential diagnosis, business
Abstract

A 50-year-old woman presented with a skin tumor on her right calf. The tumor had been noticed 20 years previously and grew to more than 60 mm in diameter. The histological findings were characterized by numerous bland xanthomatous histiocytes and a few atypical giant cells with pyknotic nuclei, although mitotic figures were few. These findings led to the diagnosis of dermatofibroma with unusual xanthomatous expression. Immunohistochemical studies using several markers for histiocytes (lysozyme, alpha 1-antitrypsin, alpha 1-antichymotrypsin and anti-CD68 antibody), anti-factor-XIIIa antibody and anti-CD34 antibody supported the diagnosis.

Published
1995
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3. Subject Index Vol. 210, 2005

Author

K. Tamaki, Katsuhiko Inagaki, R. Watanabe, Yasushi Tomita, R. Caputo, Xinwu Niu, Yohei Kitamura, Kristina Seiffert, Madoka Sato, Yumi Honda, S. Murray, E. Alessi, Masahiro Kawai, Yuki Mizuno, Hideoki Ogawa, Yutaka Hatano, N. Wasel, Huiqun Ma, June L. Traicoff, Yoko Kano, J.M. Naeyaert, Hiroki Ichikawa, Shiro Ito, T. Watanabe, Qianli Dang, Sakuhei Fujiwara, Daisuke Tsuruta, Pasqualina Ferri, Masamitsu Ishii, Masaaki Sohara, Akemi Inoue, Laura Vitiello, Steven Tien Guan Thng, Masayoshi Furukawa, H. Ihn, Luigi Racioppi, Hiroo Yokozeki, Kenneth K. Iwata, Hans-Christian Deter, Zhongwei Tian, N. van Geel, Annalisa Chiocchetti, Tamio Suzuki, Luigi Maiuri, K. Nakamura, M. Fujimoto, Marsilio Adriani, F. Cambazard, Akihiro Fujisawa, Atsushi Takahashi, Tetsuo Shiohara, Shigaku Ikeda, Christos C. Zouboulis, Greg Biesecker, Noriyuki Suzuki, Yoshiki Miyachi, Gabriele Richard, Naotomo Kambe, P. Del Giudice, P.C.M. van de Kerkhof, Kazuya Komori, Hartmut Schaechinger, Makiko Ueno, Atsushi Hatamochi, Rudolf Thurmayr, Kiyofumi Egawa, K. Ongenae, Tadashi Mio, Soji Yamazaki, Kiyoshi Nishioka, C. Tanzi, L. Brochez, Marlyanne Pol-Rodriguez, Paulina Ratajczak, O. Chosidow, K. Kragballe, N. Hattori, Michiel Appelman, R. Dummer, P. Berbis, B. Laetsch, K. Yamane, G. Hofbauer, Y. Kuwano, G. Burg, B. Crickx, Guido Pettinato, P. Bernard, Chao Liu, Arun Ramesh, Shoko Arakawa, Hui Zhou, Marjolein Wintzen, Hiromi Kobayashi, Kazushi Ishikawa, Victoria J. Lewis, Hidetaka Fujii, Umberto Dianzani, Vladimir Knezevic, Takao Tachibana, Keiko Moriwaki, Saburo Anzai, Adam S. Geyer, Junko Sowa, Maria C. Garzon, Patricia Pei-Lin Ng, William S. Millar, Yumi Matsumura, L. Dierckxsens, T. Takekoshi, Frank C. Richardson, Xianqi Zhang, P. Humbert, Galina Baibakov, Jie Feng, Andrew Yule Finlay, A.V. Marzano, Claudio Pignata, Shigeo Yokoyama, Rui Qu, W. Kempf, Koichi Nakagawa, Edwin Hilbert, Mikhail M. Galperin, Akihide Hayashi, Franck Boralevi, V. Jarlier, Hiroyuki Hashimoto, Luigi Auricchio, Klaus Weber, and H. Nakashima

Subjects
Index (economics), Statistics, Subject (documents), Dermatology, Mathematics
Published
2005
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4. A Patient with Subclinical Oculocutaneous Albinism Type 2 Diagnosed on Getting Severely Sunburned

Author

Masahiro Kawai, Tamio Suzuki, Yasushi Tomita, Shiro Ito, Katsuhiko Inagaki, and Noriyuki Suzuki

Subjects
Adult, Male, medicine.medical_specialty, genetic structures, Eye disease, DNA Mutational Analysis, Sunburn, Dermatology, Risk Assessment, Severity of Illness Index, Japan, Severity of illness, medicine, Humans, Genetic Predisposition to Disease, Allele, Alleles, Pigmentation disorder, Subclinical infection, OCA2, business.industry, Membrane Transport Proteins, medicine.disease, Oculocutaneous albinism, Albinism, Oculocutaneous, Mutation, Albinism, business, Follow-Up Studies
Abstract

P-gene-related oculocutaneous albinism (OCA2) is an autosomal recessive disorder. The phenotype is typically somewhat less severe than that of the tyrosinase-negative type (OCA1A). One of the mutations in the P gene, A481T, is associated with a mild phenotype, occasionally with no distinctive skin manifestations, which is called subclinical OCA. We present a Japanese patient having the A481T mutant allele in the P gene with subclinical oculocutaneous albinism diagnosed on getting severely sunburned. The A481T mutant allele is relatively common in the Caucasian population as well as in Japan, indicating that a number of subclinical patients of OCA2 might exist not only in Japan, but also all over the world.

Published
2005
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5. Contents Vol. 210, 2005

Author

E. Alessi, K. Tamaki, R. Dummer, Yasushi Tomita, Makiko Ueno, R. Caputo, Pasqualina Ferri, R. Watanabe, Greg Biesecker, Noriyuki Suzuki, N. Hattori, Xinwu Niu, Paulina Ratajczak, Yoshiki Miyachi, K. Nakamura, Yoko Kano, P. Bernard, T. Takekoshi, Soji Yamazaki, Gabriele Richard, Marjolein Wintzen, Hidetaka Fujii, Yumi Honda, Kenneth K. Iwata, Yutaka Hatano, K. Ongenae, Kristina Seiffert, S. Murray, Hartmut Schaechinger, H. Ihn, Luigi Racioppi, Hideoki Ogawa, Marlyanne Pol-Rodriguez, Jie Feng, T. Watanabe, Andrew Yule Finlay, Akihide Hayashi, Hans-Christian Deter, Masahiro Kawai, June L. Traicoff, Tamio Suzuki, Michiel Appelman, Atsushi Takahashi, Christos C. Zouboulis, Hiroyuki Hashimoto, Masayoshi Furukawa, Kiyofumi Egawa, Hiroo Yokozeki, Daisuke Tsuruta, A.V. Marzano, Claudio Pignata, G. Hofbauer, Edwin Hilbert, Shiro Ito, Hui Zhou, Shigeo Yokoyama, Steven Tien Guan Thng, Mikhail M. Galperin, Sakuhei Fujiwara, P. Berbis, B. Laetsch, K. Yamane, Hiroki Ichikawa, Qianli Dang, J.M. Naeyaert, Rui Qu, Masamitsu Ishii, Kazuya Komori, Katsuhiko Inagaki, N. van Geel, Takao Tachibana, Keiko Moriwaki, Frank C. Richardson, Xianqi Zhang, Umberto Dianzani, Vladimir Knezevic, Luigi Auricchio, Y. Kuwano, Adam S. Geyer, Luigi Maiuri, V. Jarlier, B. Crickx, Chao Liu, Yohei Kitamura, Hiromi Kobayashi, Franck Boralevi, Arun Ramesh, Zhongwei Tian, Tetsuo Shiohara, Masaaki Sohara, Shigaku Ikeda, Akihiro Fujisawa, Kazushi Ishikawa, Shoko Arakawa, N. Wasel, W. Kempf, Rudolf Thurmayr, William S. Millar, Yuki Mizuno, M. Fujimoto, Marsilio Adriani, Tadashi Mio, Madoka Sato, P. Humbert, Koichi Nakagawa, F. Cambazard, Huiqun Ma, Kiyoshi Nishioka, C. Tanzi, Yumi Matsumura, L. Dierckxsens, L. Brochez, Klaus Weber, H. Nakashima, Naotomo Kambe, P. Del Giudice, P.C.M. van de Kerkhof, Annalisa Chiocchetti, Galina Baibakov, Victoria J. Lewis, G. Burg, Guido Pettinato, Akemi Inoue, Laura Vitiello, Atsushi Hatamochi, O. Chosidow, K. Kragballe, Saburo Anzai, Junko Sowa, Maria C. Garzon, and Patricia Pei-Lin Ng

Subjects
Dermatology
Published
2005
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6. Erratum / Book Review

Author

R. Aquaron, D. O’Sullivan, K.H. Holubar, S. Mach-Pascual, Pompeo Cassano, P. Disdier, R.D.R. Camp, Günther F.L. Hofbauer, Andreas Blum, Gisela Metzler, N. Binder, B.S. Ramakrishna, Akira Kawada, A.J. Kanwar, R. Viraben, J. Heilbrunner, Noboru Murakami, Silvia Ferrucci, P.A. Veys, Tadashi Tezuka, Tamio Suzuki, Mario Corbellino, Jürgen Bauer, Ralph M. Trüeb, Jean-François Rossi, Matthias Augustin, Johannes Ott, Mysore Venkataram, H. Seidl, C. Weiller-Merli, Lucia Brambilla, Masako Mizoguchi, J.-H. Saurat, Y. Nordmann, D. Tsambaos, Osamu Koro, R. Panizzon, Stella Fatović-Ferenčić, F. Cottoni, Yasushi Tomita, Kenji Yajima, Gernot Rassner, Daniele Bollero, M.J. Dillon, Christine Uhlemann, Jann Lübbe, Peter Itin, Bénédicte Thédenat, M.V. Masala, S. Boulinguez, A. Hofer, W. Arp, X. Pache, Jean-Jacques Guilhou, M.C. Brouard, G. Burg, R. Bouabdallah, B. Granel, Eishin Morita, Peter Scheib, C.A. Holden, J. Serratrice, Thorsten Burger, Barta U, Kunihiko Tamaki, S. Fossati, A.Y. Finlay, Marie Claude Marguery, H.-P. Zahradnik, J.I. Harper, S. Kaddu, P.L. Newman, S. Kaur, Alessandra Clemente, Syoso Yamamoto, R. Hubert Laeng, H. Kerl, Tamihiro Kawakami, Emilio Berti, J. Berth-Jones, Ruri Matsunaga, P.J. Weiller, I. Worret, Koichiro Nakamura, F. Al-Hilli, Reinhard Dummer, L. Swiader, Jacques Bazex, Yoshinori Aragane, Maurizio Stella, Masato Kashima, Yoshinao Soma, Uwe Wollina, Peter Wolf, Ayumi Yajima, Robert Navarro, F. Loche, Claus Garbe, Olivier Dereure, Giusy Giorio, U. Bösch, Vinicio Boneschi, Ina Zschocke, A.G. Lambiris, P.H. Bloch, Akiko Imaizumi, C. Prins, Max A. Spycher, Brigitte Albes, Carlo Parravicini, Peter Oelzner, G. Tedde, Karl Holubar, J.-O. Andreas, G.P. Thami, Ayumi Adachi, and Kurt Fritzsche

Subjects
Dermatology
Published
2001
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7. In Memoriam / Announcements

Author

Yukitoshi Yamaguchi, W. Skarabis, R.J.A. Wanders, H.S. Zackheim, A.G. Knight, Z. Demetriou, Noriaki Shinomiya, K. Nakamura, Jean-Charles Piette, K. Peris, A. Carrassi, Sylvie Legrain, T. Murakami, B. Bjarnason, G. Orecchia, J. Rey, Felix Heitzmann, Masakazu Asahi, Ryuzo Saito, Kanako Kikuchi, P. Elsner, Osamu Yamamoto, B. Granel, S. Dhar, A. Sardella, Masahisa Watanabe, Margit Nindl, A. Katsambas, G. Sacerdoti, Marie-Sylvie Doutre, Caroline Roudier-Pujol, J. Economidou, Itsuro Matsuo, S. Yano, Masayuki Amagai, O. Avcı, Leila Jeskanen, G. Kaya, Arja-Leena Kariniemi, Anne Auperin, S. Chimenti, D. Degiannis, Marie Beylot Barry, Hiroko Gomi, Hiromi Kazama, François Laurent, G.K. Patel, F. Châtillon, Peter Itin, G. Lodi, M. Yoshida, C. Bez, T. Fischer, Stubb S, P.J. Weiller, Takaaki Kobayashi, Emilio Berti, C. Beylot, P.M. Steijlen, M.A. de Rie, Kayo Yamaguchi, Tamihiro Kawakami, J. Cilliers, Hachiro Tagami, E. Flosadóttir, S.E. Shephard, G. Avgerinou, R.G. Panizzon, Ikuo Murata, Tapio Rantanen, Xavier Roques, M.A.A.P. Willemsen, Yasushi Tomita, A. Rebora, Elvio Alessi, Thiem Nguyen, G. Kolde, W. Sterry, Nobuko Tabata, Yoshinori Miyamura, A.T. Güneş, H. Audring, Peter Schiller, J. Stock, L. Presenti, Misako Tanaka, C. de Beer, Tugutoshi Aoki, V. Marlière, Patrick Blanco, Muneo Tanita, Claire Beylot, C. Romano, E. Ellidokuz, Masahiro Hara, J. Serratrice, A. Oga, I. Şimşek, H. Ihn, A. Denizot, J.J. Rotteveel, Yoichi Nagata, Marie-Fançoise Avril, B. Büyükgebiz, Kentaro Yoshinaga, A. Köhler, C. Chizzolini, A. Vareltzidis, Angelo V. Marzano, Ellen Benhamou, A. Della Volpe, R.U. Peter, Eriko Nakamura, P. Berbis, Jun Matsunaga, Pierre Duvillard, M. Beylot-Barry, M. Muto, M. Fazio, Masutaka Furue, K. Tamaki, S.M. Clark, S.K. Todi, Gilles Raguin, M.-S. Doutre, Yoshinao Fujikawa, L. Muscardin, T. Shimizu, F. Drago, E. Ranieri, C. Hauser, K. Psarra, J. Barkis, L. Lupica, Ichiro Katayama, P. Disdier, M.M.U. Chowdhury, Akira Kawada, L. Massai, H. Okochi, Sandra Ly, H. Gall, Miwako Dakeishi-Hara, Hiroaki Aoyama, Fumihide Ogawa, Antti Lauerma, Hirotsugu Yamanouchi, M. Worm, Bernhard Stamm, and L. Borradori

Subjects
medicine.medical_specialty, Economics, medicine, Dermatology
Published
1999
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8. Hereditary Benign Telangiectasia: A Congenital Type

Author

Hachiro Tagami, Mariko Watanabe, and Yasushi Tomita

Subjects
Adult, Male, Leg, Pathology, medicine.medical_specialty, Erythema, business.industry, Hereditary benign telangiectasia, Infant, Dermatology, Child, Preschool, Humans, Medicine, Female, Telangiectasis, Congenital disease, medicine.symptom, business, Telangiectasia
Abstract

Hereditary benign telangiectasia (HBT) is inherited in an autosomal dominant fashion, and in all the cases reported in the past it developed after birth. We describe 3 congenital cases of HBT in the same Japanese family: a 29-year-old father and his 5-month- and 2-year-old daughters have had scattered erythematous patches of various sizes in diameter since birth.

Published
1990
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9. New Primary Malignant Melanoma, Epidermotropism and Indian-File Arrangement of Metastatic Tumor Cells in a Case with Intransit Metastases of Acral Type of Malignant Melanoma

Author

Yasushi Tomita, Hachiro Tagami, Toshiro Demitsu, and Taizo Kato

Subjects
Pathology, medicine.medical_specialty, Skin Neoplasms, Dermatology, Malignant transformation, Metastasis, Dermis, Biopsy, medicine, Humans, Melanoma, Aged, Skin, medicine.diagnostic_test, business.industry, Papule, Toes, Melanocytic nevus, medicine.disease, Dissection, medicine.anatomical_structure, Thigh, Melanocytes, Female, medicine.symptom, business
Abstract

Multiple malignant melanocytic lesions developed on a localized area of the thigh in an 80-year-old woman 3 years after excision of a primary malignant melanoma on the left second toe and dissection of left inguinal lymph nodes. Biopsy specimens obtained from 2 small pigmented macules revealed the histologic features of new primary lesions, simulating that of the primary lesion on the toe; no tumor cells were found within vessel lumina. A brown-black papule neighboring one of the macules histologically resembled compound type of melanocytic nevus, but the tumor cells compressed thinned epidermis with focal epidermotropism. Other papules, whose color ranged from light brown to reddish brown, showed metastatic tumor cells only in the dermis. In 3 of them, individual tumor cells were lined up along the collagen bundles, showing an ‘Indian-file’ arrangement. Such a combination of various histologic features in a case of intransit metastases of acral type of melanoma has not been reported in the literature.

Published
1986
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10. Mechanisms for Hyperpigmentation in Postinflammatory Pigmentation, Urticaria pigmentosa and Sunburn

Author

Hachiro Tagami, Kazuhisa Maeda, and Yasushi Tomita

Subjects
medicine.medical_specialty, Time Factors, Tyrosinase, Sunburn, Skin Pigmentation, Arachidonic Acids, Dermatology, Melanocyte, Melanin, Urticaria Pigmentosa, medicine, Humans, Cells, Cultured, Cholecalciferol, Skin, Inflammation, Melanins, integumentary system, Histamine metabolism, business.industry, medicine.disease, Hyperpigmentation, medicine.anatomical_structure, Melanocytes, Urticaria pigmentosa, medicine.symptom, business, Postinflammatory hyperpigmentation, Histamine
Abstract

Our in vitro studies demonstrate that normal human epidermal melanocytes become swollen and more dendritic with an increase in amount of immunoreactive tyrosinase when they are cultured for several days with arachidonic acid metabolites vitamin D3 or histamine. From these data we propose the following possible mechanisms for hyperpigmentations noted at postinflammatory sites and suntanned areas as well as at skin lesions of urticaria pigmentosa. Arachidonic acid metabolites and histamine, which are found in increased amounts in inflammatory skin, are thought to play a key role in the induction of postinflammatory hyperpigmentation. In sunburnt skin the increased proinflammatory mediators, particularly arachidonic acid metabolites, are also thought to stimulate melanocytes in the production of hyperpigmentation. Thus tanning after sun exposure may be induced not only by the effect of vitamin D3 and direct UV irradiation on the melanocytes but also by the effect of various arachidonic acid metabolites which are increased in sunburnt skin. Mast cells massively proliferate in the skin lesions of urticaria pigmentosa. Thus hyperpigmentation in the skin lesions of urticaria pigmentosa is quite likely to be induced by the chemical mediators, including histamine and leukotrienes, that are released from these cells.

Published
1989
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