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The term "potentially inadequate medication" (PIM) describes medications or active substances that should not be prescribed to older persons because of their adverse effects profile. Such relative contraindications should always be considered in the overall context and in view of comorbidities and further medications. The PRISCUS 2.0 list was published recently--a revised version of a PIM list for the German pharmaceutical market (1). When considering the number of older patients in the healthcare system for whom these medications may pose risks, this topic is more topical than ever. Thus far only few published data exist on the prevalence of PIMs and their development as well as on the PIM substances most commonly prescribed in primary care in Germany. [ABSTRACT FROM AUTHOR]