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Climate change continues to exacerbate social and economic development challenges in local communities the world over. This paper advances a human development approach to climate resilience innovations, showing how local innovation initiatives can be conduits for increased equity, agency, efficiency and sustainability vis-à-vis effective responses to climate impacts. Based on a scoping review of literature (journal articles, books, theses, occasional papers etc.), and through a discussion of four case studies focused on technological and institutional innovations in selected rural South African communities, a major finding is that local innovation initiatives vis-à-vis livelihoods are laden with opportunities for improved social, economic and ecological well-being. Appreciating and supporting these local innovations will open up viable and transformative pathways towards effectively responding to the impacts of climate change and variability. The paper contributes to an interdisciplinary integration of innovation and climate change research by exploring climate resilience through a transformative human development lens. [ABSTRACT FROM AUTHOR]