Search

Your search keyword '"Sun, Li"' showing total 1 results
1 results on '"Sun, Li"'

1. SmLMWPTP, a teleost low molecular weight protein tyrosine phosphatase, inhibits the immune response of peripheral blood leukocytes in a manner that depends on the conserved P-loop.

Author

Zhang, Jian, Chen, Ling, and Sun, Li

Subjects
*MOLECULAR weights, *LEUCOCYTES, *PROTEIN-tyrosine phosphatase, *IMMUNE response, *ENZYME activation, *GENE expression, *GENETIC mutation
Abstract

Highlights: [•] SmLMWPTP is a low molecular weight protein tyrosine phosphatase from turbot. [•] rSmLMWPTP exhibited optimum tyrosine phosphatase activity at pH 5 and 50°C. [•] Peripheral blood leukocytes (PBL) infected by pathogen expressed and secreted SmLMWPTP. [•] rSmLMWPTP reduced the biological activity, gene expression, and phagocytosis of PBL. [•] Mutation of the P-loop sequence abolished the regulatory effect of SmLMWPTP on PBL. [ABSTRACT FROM AUTHOR]

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results