18 results
Search Results
2. Use of the Dyskinesia Impairment Scale in non-ambulatory dyskinetic cerebral palsy.
- Author
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Haberfehlner, Helga, Bonouvrié, Laura A, Boeschoten, Karin, Fleuren, Sabine, Monbaliu, Elegast, Becher, Jules G, Vermeulen, R Jeroen, and Buizer, Annemieke I
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CEREBRAL palsy ,DYSKINESIAS ,PEOPLE with cerebral palsy ,DISABILITIES ,RANDOMIZED controlled trials ,RESEARCH ,MUSCLE relaxants ,SPINAL injections ,RESEARCH methodology ,MOVEMENT disorders ,DISABILITY evaluation ,EVALUATION research ,MEDICAL cooperation ,SEVERITY of illness index ,TREATMENT effectiveness ,COMPARATIVE studies ,BACLOFEN - Abstract
Aim: To assess the responsiveness, concurrent validity, and feasibility of the Dyskinesia Impairment Scale (DIS) in non-ambulatory patients with dyskinetic cerebral palsy (CP).Method: The study is a secondary analysis of data collected in the IDYS trial, a randomized controlled trial on the effects of intrathecal baclofen (ITB). The DIS and Barry-Albright Dystonia Scale (BADS) were conducted at baseline and after 3 months of ITB or placebo treatment. Responsiveness was assessed by comparing the effect sizes and correlation of change after treatment between the DIS and BADS. Concurrent validity was evaluated by assessing the correlations between scales. Feasibility was evaluated for each DIS item by the number of participants who successfully accomplished the item.Results: Thirty-three non-ambulatory patients (9 females, 24 males) with dyskinetic CP (ITB-treated: n=17, mean [SD] age: 14y 1mo [4y 1mo]; placebo-treated: n=16, mean [SD] age: 14y 7mo [4y]) were included in the study. The effect sizes for BADS and DIS were similar in The ITB-treated group (-0.29 and -0.22 respectively). Changes after treatment on the DIS dystonia subscale correlated with changes on the BADS (r=0.64; p<0.001). The DIS dystonia subscale and BADS correlated at baseline and follow-up (r=0.78; p<0.001 and r=0.79; p<0.001). Not all DIS activity items could be performed in this sample of patients.Interpretation: For non-ambulatory patients with dyskinetic CP, the responsiveness of the DIS equalled the responsiveness of BADS. Concurrent validity was adequate. Feasibility for activity items was restricted in patients with severe dyskinetic CP.What This Paper Adds: The Dyskinesia Impairment Scale (DIS) and Barry-Albright Dystonia Scale showed similar responsiveness in non-ambulatory patients with dyskinetic cerebral palsy (CP). No floor or ceiling effect was observed for DIS in non-ambulatory participants. The concurrent validity of DIS was adequate in non-ambulatory participants. Patients with dyskinetic CP in Gross Motor Function Classification System levels IV and V could not perform all DIS activity items. [ABSTRACT FROM AUTHOR]- Published
- 2020
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3. Long-term effects of repeated botulinum neurotoxin A, bimanual training, and splinting in young children with cerebral palsy.
- Author
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Lidman, Git R M, Nachemson, Ann K, Peny‐Dahlstrand, Marie B, Himmelmann, Kate M E, and Peny-Dahlstrand, Marie B
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BOTULINUM A toxins ,CHILDREN with cerebral palsy ,OCCUPATIONAL therapy for children ,BOTULINUM toxin ,OCCUPATIONAL therapy ,CEREBRAL palsy treatment ,RESEARCH ,MUSCLE relaxants ,RESEARCH methodology ,SPLINTS (Surgery) ,EVALUATION research ,MEDICAL cooperation ,TREATMENT effectiveness ,COMPARATIVE studies ,HAND ,RESEARCH funding ,COMBINED modality therapy ,CEREBRAL palsy ,LONGITUDINAL method ,MOTOR ability - Abstract
Copyright of Developmental Medicine & Child Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
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4. Reliability and responsiveness of the Jebsen-Taylor Test of Hand Function and the Box and Block Test for children with cerebral palsy.
- Author
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Araneda, Rodrigo, Ebner‐Karestinos, Daniela, Paradis, Julie, Saussez, Geoffroy, Friel, Kathleen M, Gordon, Andrew M, Bleyenheuft, Yannick, and Ebner-Karestinos, Daniela
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CHILDREN with cerebral palsy ,INTRACLASS correlation ,STATISTICAL reliability ,MOTOR ability ,TEST reliability ,ARM ,CEREBRAL palsy ,COMPARATIVE studies ,FUNCTIONAL assessment ,NEUROPSYCHOLOGICAL tests ,RESEARCH methodology ,MEDICAL cooperation ,RESEARCH ,RESEARCH evaluation ,RESEARCH funding ,EVALUATION research ,TREATMENT effectiveness ,RETROSPECTIVE studies - Abstract
Copyright of Developmental Medicine & Child Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
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5. Gait analysis for individually tailored interdisciplinary interventions in children with cerebral palsy: a randomized controlled trial.
- Author
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Rasmussen, Helle M, Pedersen, Niels W, Overgaard, Søren, Hansen, Lars K, Dunkhase‐Heinl, Ulrike, Petkov, Yanko, Engell, Vilhelm, Holsgaard‐Larsen, Anders, Dunkhase-Heinl, Ulrike, and Holsgaard-Larsen, Anders
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CHILDREN with cerebral palsy ,RANDOMIZED controlled trials ,ORTHOPEDIC surgery ,QUALITY of life ,PHYSICAL therapy for children ,PHYSICAL therapy ,CEREBRAL palsy treatment ,CEREBRAL palsy ,COMPARATIVE studies ,GAIT in humans ,LONGITUDINAL method ,ORTHOPEDIC apparatus ,RESEARCH methodology ,MEDICAL cooperation ,RESEARCH ,STATISTICAL sampling ,EVALUATION research ,TREATMENT effectiveness - Abstract
Copyright of Developmental Medicine & Child Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
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6. Long-term muscle changes after hamstring lengthening in children with bilateral cerebral palsy.
- Author
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Salami, Firooz, Brosa, Julia, Van Drongelen, Stefan, Klotz, Matthias C M, Dreher, Thomas, Wolf, Sebastian I, and Thielen, Mirjam
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CHILDREN with cerebral palsy ,HAMSTRING muscle ,CEREBRAL palsy ,MUSCLES ,BIOLOGICAL models ,COMPARATIVE studies ,KINEMATICS ,RESEARCH methodology ,MEDICAL cooperation ,RESEARCH ,TIME ,EVALUATION research ,TREATMENT effectiveness ,RETROSPECTIVE studies - Abstract
Copyright of Developmental Medicine & Child Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
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7. Medial gastrocnemius volume and echo-intensity after botulinum neurotoxin A interventions in children with spastic cerebral palsy.
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Schless, Simon‐Henri, Cenni, Francesco, Bar‐On, Lynn, Hanssen, Britta, Kalkman, Barbara, O'brien, Thomas, Aertbeliën, Erwin, Van Campenhout, Anja, Molenaers, Guy, Desloovere, Kaat, Schless, Simon-Henri, and Bar-On, Lynn
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BOTULINUM toxin ,CHILDREN with cerebral palsy ,NATURAL history ,MULTIPLE regression analysis ,CEREBRAL palsy ,ANTHROPOMETRY ,COMPARATIVE studies ,INTRAMUSCULAR injections ,LEG ,LONGITUDINAL method ,RESEARCH methodology ,MEDICAL cooperation ,MUSCLE relaxants ,RESEARCH ,RESEARCH funding ,SPASTICITY ,ULTRASONIC imaging ,THREE-dimensional imaging ,EVALUATION research ,TREATMENT effectiveness ,SKELETAL muscle ,DISEASE complications - Abstract
Copyright of Developmental Medicine & Child Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
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8. Muscle volume alterations after first botulinum neurotoxin A treatment in children with cerebral palsy: a 6-month prospective cohort study.
- Author
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Alexander, Caroline, Elliott, Catherine, Valentine, Jane, Stannage, Katherine, Bear, Natasha, Donnelly, Cyril J., Shipman, Peter, and Reid, Siobhan
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BOTULINUM A toxins ,CEREBRAL palsy treatment ,MUSCLE abnormalities ,TREATMENT effectiveness ,COHORT analysis ,ANTHROPOMETRY ,BOTULINUM toxin ,CEREBRAL palsy ,COMPARATIVE studies ,EXERCISE tests ,HYPERTROPHY ,INTRAMUSCULAR injections ,LEG ,LONGITUDINAL method ,RESEARCH methodology ,MEDICAL cooperation ,MUSCLE relaxants ,RESEARCH ,SPASTICITY ,EVALUATION research ,ATROPHY ,SKELETAL muscle ,DISEASE complications - Abstract
Copyright of Developmental Medicine & Child Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2018
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9. Responsiveness of the ACTIVLIM-CP questionnaire: measuring global activity performance in children with cerebral palsy.
- Author
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Paradis, Julie, Arnould, Carlyne, Thonnard, Jean‐Louis, Houx, Laëtitia, Pons‐Becmeur, Christelle, Renders, Anne, Brochard, Sylvain, Bleyenheuft, Yannick, Thonnard, Jean-Louis, and Pons-Becmeur, Christelle
- Subjects
PEDIATRIC intensive care ,ACTIVITIES of daily living ,BOTULINUM A toxins ,QUESTIONNAIRES ,QUALITY of life ,CEREBRAL palsy treatment ,BOTULINUM toxin ,CEREBRAL palsy ,COMPARATIVE studies ,INJECTIONS ,LONGITUDINAL method ,RESEARCH methodology ,MEDICAL cooperation ,MOTOR ability ,MUSCLE relaxants ,PHYSICAL therapy ,RESEARCH ,RESEARCH funding ,EVIDENCE-based medicine ,PROFESSIONAL practice ,EVALUATION research ,TREATMENT effectiveness ,SEVERITY of illness index ,DIAGNOSIS - Abstract
Copyright of Developmental Medicine & Child Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2018
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10. Evolution of self-care and functional mobility after single-event multilevel surgery in children and adolescents with spastic diplegic cerebral palsy.
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Dequeker, Griet, Van Campenhout, Anja, Feys, Hilde, and Molenaers, Guy
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CHILDREN with cerebral palsy ,DEVELOPMENTAL disabilities ,PEDIATRIC orthopedics ,MOVEMENT disorders in children ,QUALITY of life ,CEREBRAL palsy ,COMPARATIVE studies ,FUNCTIONAL assessment ,RESEARCH methodology ,MEDICAL cooperation ,NEUROSURGERY ,PROGNOSIS ,QUESTIONNAIRES ,RESEARCH ,HEALTH self-care ,SPASTICITY ,TIME ,EVALUATION research ,TREATMENT effectiveness ,RETROSPECTIVE studies - Abstract
Copyright of Developmental Medicine & Child Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2018
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11. Pharmacological and neurosurgical interventions for managing dystonia in cerebral palsy: a systematic review.
- Author
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Fehlings, Darcy, Brown, Leah, Harvey, Adrienne, Himmelmann, Kate, Lin, Jean‐Pierre, Macintosh, Alexander, Mink, Jonathan W., Monbaliu, Elegast, Rice, James, Silver, Jessica, Switzer, Lauren, Walters, Ilana, and Lin, Jean-Pierre
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NEUROSURGERY ,TREATMENT of dystonia ,CEREBRAL palsy treatment ,SYSTEMATIC reviews ,TREATMENT effectiveness ,MUSCLE relaxants ,BACLOFEN ,CEREBRAL palsy ,COMPARATIVE studies ,DYSTONIA ,RESEARCH methodology ,MEDICAL cooperation ,RESEARCH ,EVALUATION research ,DEEP brain stimulation ,DISEASE complications ,THERAPEUTICS - Abstract
Copyright of Developmental Medicine & Child Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2018
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12. Communication disorders in young children with cerebral palsy.
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Pennington, Lindsay, Dave, Mona, Rudd, Jennifer, Hidecker, Mary Jo Cooley, Caynes, Katy, and Pearce, Mark S
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CHILDREN with cerebral palsy ,COMMUNICATIVE disorders ,TELECOMMUNICATION systems ,ORAL communication ,SPEECH therapy ,TREATMENT of communicative disorders ,RESEARCH ,RESEARCH methodology ,LANGUAGE & languages ,DISABILITY evaluation ,EVALUATION research ,MEDICAL cooperation ,TREATMENT effectiveness ,COMPARATIVE studies ,COMMUNICATION ,RESEARCH funding ,CEREBRAL palsy ,SPEECH ,DISEASE complications - Abstract
Aim: To test the prediction of communication disorder severity at 5 years of age from characteristics at 2 years for children with cerebral palsy (CP) whose communication is giving cause for concern.Method: In this cohort study, 77 children (52 males; 25 females) with communication difficulties and CP were visited at home at 2 (mean 2y 4mo; SD 3mo) and 5 (mean 5y 5mo; SD 4mo) years of age. Information on the type and distribution of motor disorder, seizures, gross and fine motor function, hearing, and vision were collected from medical notes. Non-verbal cognition, language comprehension, language expression, spoken vocabulary, and methods of communication were assessed directly at age 2 years. At 5 years, communication and speech function were rated using the Communication Function Classification System (CFCS), Functional Communication Classification System (FCCS), and Viking Speech Scale (VSS).Results: In multivariable regression models, CP type, Gross Motor Function Classification System level, vision, the amount of speech understood by strangers, non-verbal cognition, and number of consonants produced at age 2 years predicted the CFCS level at age 5 years (R2 =0.54). CP type, Manual Ability Classification System level, amount of speech understood, vision, and number of consonants predicted the FCCS level (R2 =0.49). CP type, amount of speech understood by strangers, and number of consonants predicted the VSS level (R2 =0.50).Interpretation: Characteristics at 2 years of age predict communication and speech performance at 5 years, and should inform referral to speech and language therapy. [ABSTRACT FROM AUTHOR]- Published
- 2020
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13. Energy consumption does not change after selective dorsal rhizotomy in children with spastic cerebral palsy.
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Zaino, Nicole L, Steele, Katherine M, Donelan, J Maxwell, and Schwartz, Michael H
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CHILDREN with cerebral palsy ,ENERGY consumption ,RHIZOTOMY ,WALKING speed ,ENERGY metabolism ,RESEARCH ,OXYGEN consumption ,RESEARCH methodology ,RETROSPECTIVE studies ,EVALUATION research ,MEDICAL cooperation ,SPASTICITY ,TREATMENT effectiveness ,COMPARATIVE studies ,WALKING ,RESEARCH funding ,CEREBRAL palsy ,DISEASE complications - Abstract
Aim: To determine whether energy consumption changes after selective dorsal rhizotomy (SDR) among children with cerebral palsy (CP).Method: We retrospectively evaluated net nondimensional energy consumption during walking among 101 children with bilateral spastic CP who underwent SDR (59 males, 42 females; median age [5th centile, 95th centile] 5y 8mo [4y 2mo, 9y 4mo]) compared to a control group of children with CP who did not undergo SDR. The control group was matched by baseline age, spasticity, and energy consumption (56 males, 45 females; median age [5th centile, 95th centile] 5y 8mo [4y 1mo, 9y 6mo]). Outcomes were compared at baseline and follow-up (SDR: mean [SD] 1y 7mo [6mo], control: 1y 8mo [8mo]).Results: The SDR group had significantly greater decreases in spasticity compared to matched controls (-42% SDR vs -20% control, p<0.001). While both groups had a modest reduction in energy consumption between visits (-12% SDR, -7% control), there was no difference in change in energy consumption (p=0.11) or walking speed (p=0.56) between groups.Interpretation: The SDR group did not exhibit greater reductions in energy consumption compared to controls. The SDR group had significantly greater spasticity reduction, suggesting that spasticity had minimal impact on energy consumption during walking in CP. These results support prior findings that spasticity and energy consumption decrease with age in CP. Identifying matched control groups is critical for outcomes research involving children with CP to account for developmental changes. [ABSTRACT FROM AUTHOR]- Published
- 2020
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14. Deep brain stimulation reduces pain in children with dystonia, including in dyskinetic cerebral palsy.
- Author
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Perides, Sarah, Lin, Jean‐Pierre, Lee, Geraldine, Gimeno, Hortensia, Lumsden, Daniel E, Ashkan, Keyoumars, Selway, Richard, Kaminska, Margaret, and Lin, Jean-Pierre
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DEEP brain stimulation ,CEREBRAL palsy ,PAIN management ,DROOLING ,SUBTHALAMIC nucleus ,MOVEMENT disorders ,PAIN ,MUSCLE contraction ,RESEARCH ,PAIN measurement ,RESEARCH methodology ,DYSTONIA ,EVALUATION research ,MEDICAL cooperation ,TREATMENT effectiveness ,SEVERITY of illness index ,COMPARATIVE studies ,QUESTIONNAIRES ,RESEARCH funding ,DISEASE complications - Abstract
Aim: To establish the prevalence of dystonic pain in children and their response to deep brain stimulation (DBS).Method: Dystonic pain was assessed in a cohort of 140 children, 71 males and 69 females, median age 11 years 11 months (range 3y-19y 1mo), undergoing DBS in our centre over a period of 10 years. The cohort was divided into aetiological dystonia groups: 1a, inherited; 1b, heredodegenerative; 2, acquired; and 3, idiopathic. Motor responses were measured with the Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS).Results: Dystonic pain was identified in 63 (45%) patients, 38% of whom had a diagnosis of cerebral palsy (CP). Dystonic pain improved in 90% of children and in all aetiological subgroups 1 year after DBS, while the BFMDRS motor score improved in 70%. Statistically significant improvement (p<0.01) was noted for the whole cohort on the Numerical Pain Rating Scale (n=27), Paediatric Pain Profile (n=17), and Caregivers Priorities and Child Health Index of Life with Disabilities questionnaire (n=48). There was reduction of pain severity, frequency, and analgesia requirement. Findings were similar for the whole cohort and aetiological subgroups other than the inherited heredodegenerative group where the improvement did not reach statistical significance.Interpretation: Dystonic pain is frequent in children with dystonia, including those with CP, who undergo DBS; this can be an important, realizable goal of surgery irrespective of aetiology. We encourage the use of multimodal approach in pain research to reduce the risk of bias. [ABSTRACT FROM AUTHOR]- Published
- 2020
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15. Intensive upper- and lower-extremity training for children with bilateral cerebral palsy: a quasi-randomized trial.
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Bleyenheuft, Yannick, Ebner‐Karestinos, Daniela, Surana, Bhavini, Paradis, Julie, Sidiropoulos, Alexis, Renders, Anne, Friel, Kathleen M, Brandao, Marina, Rameckers, Eugene, and Gordon, Andrew M
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CEREBRAL palsy ,MOVEMENT disorders in children ,RANDOMIZED controlled trials ,BODY movement ,ABNORMALITIES in the anatomical extremities ,ARM ,CEREBRAL dominance ,COMPARATIVE studies ,POSTURAL balance ,EXERCISE therapy ,HAND ,LEG ,LONGITUDINAL method ,RESEARCH methodology ,MEDICAL cooperation ,MOTOR ability ,RESEARCH ,WALKING ,PILOT projects ,EVALUATION research ,TREATMENT effectiveness ,SEVERITY of illness index - Abstract
Aim: An approach that simultaneously engages both the upper and lower extremities, hand-arm bimanual intensive therapy including lower extremity (HABIT-ILE), has recently demonstrated improvements in upper and lower extremities in children with unilateral cerebral palsy (CP). It is not known whether children with bilateral CP would benefit from this approach. The aim of this study was to examine the efficacy of HABIT-ILE in children with bilateral CP.Method: A quasi-randomized trial design was used, whereby 20 participants (age 6-15y, Gross Motor Function Classification System levels II-IV, Manual Ability Classification System levels I-III) were assigned to a treatment (HABIT-ILE) or a comparison group in the order in which they were enrolled. Children in the HABIT-ILE group were assessed before and after 84 hours of intervention over 13 days, as well as at 3 months' follow-up. Children in the comparison group were assessed at the same time points. Children in both groups were assessed using the Gross Motor Function Measure (GMFM-66) and ABILHAND-Kids (primary measures), and six secondary measures.Results: A group×test session interaction indicated significant improvements in the HABIT-ILE group as assessed by the GMFM-66, lower-extremity performance (6-Minute Walk Test; Pediatric Balance Scale), functional upper-extremity abilities (ABILHAND-Kids/Pediatric Evaluation of Disability Inventory), and the dexterity of the less affected upper extremity.Conclusion: HABIT-ILE is efficacious for improving both upper- and lower-extremity function in children with bilateral CP. [ABSTRACT FROM AUTHOR]- Published
- 2017
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16. 'Remind-to-move' treatment versus constraint-induced movement therapy for children with hemiplegic cerebral palsy: a randomized controlled trial.
- Author
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Dong, Vicky Anqin, Fong, Kenneth N K, Chen, Yun‐Feng, Tseng, Stella S W, and Wong, Louisa M S
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MOVEMENT therapy ,CEREBRAL palsy treatment ,MIND & body therapies ,MOVEMENT education ,EXERCISE therapy ,MOVEMENT disorders ,DEVELOPMENTAL disabilities ,ARM ,CEREBRAL palsy ,COMPARATIVE studies ,HEMIPLEGIA ,RESEARCH methodology ,MEDICAL cooperation ,NONPARAMETRIC statistics ,HEALTH outcome assessment ,RESEARCH ,EVALUATION research ,BODY movement ,RANDOMIZED controlled trials ,ACCELEROMETRY ,TREATMENT effectiveness ,BLIND experiment ,DISEASE complications - Abstract
Aim: To evaluate 'remind-to-move' (RTM) treatment by comparing it with constraint-induced movement therapy (CIMT) and conventional rehabilitation of the upper extremity in children with hemiplegic cerebral palsy (CP).Method: Seventy-three children (44 males, 29 females; mean age 11y 8mo, standard deviation [SD] 3y 1mo) - with 20, 38, and 15 in Manual Ability Classification System levels I, II, and III respectively - were recruited from three special schools and randomly selected for an RTM (n=25) or CIMT (n=24) programme (for 75h over 3wks) or for conventional rehabilitation (n=24). The Jebsen-Taylor Hand Function Test, the Bruininks-Oseretsky Test of Motor Proficiency (Subtest 3), the Caregiver Functional Use Survey, and arm movement duration captured by accelerometers were used at the baseline, post-test, and 1-month and 3-month follow-ups.Results: Both the RTM and CIMT treatments achieved significant gains in manual capacities and spontaneous hand use immediately after the intervention compared with conventional rehabilitation, but there were no significant differences between the two interventions.Interpretation: The RTM treatment demonstrated similar therapeutic effects with CIMT in manual dexterity and functional hand use, but both interventions were superior to conventional rehabilitation. RTM is recommended as an alternative treatment for the hemiplegic upper extremity in children with CP. [ABSTRACT FROM AUTHOR]- Published
- 2017
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17. Botulinum neurotoxin treatment in children with cerebral palsy: validation of a needle placement protocol using passive muscle stretching and relaxing.
- Author
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Warnink‐Kavelaars, Jessica, Vermeulen, R Jeroen, Buizer, Annemieke I, and Becher, Jules G
- Subjects
CEREBRAL palsy treatment ,BOTULINUM toxin ,THERAPEUTICS ,CHILDREN with cerebral palsy ,TREATMENT effectiveness ,ELECTRIC stimulation ,MEDICAL protocols ,CEREBRAL palsy ,COMPARATIVE studies ,INJECTIONS ,INTRAMUSCULAR injections ,RESEARCH methodology ,MEDICAL cooperation ,MUSCLE relaxants ,RESEARCH ,EVALUATION research ,SKELETAL muscle - Abstract
Aim: To validate a detailed intramuscular needle placement protocol using passive muscle stretching and relaxing for botulinum neurotoxin type A (BoNT-A) treatment in the lower extremity of children with spastic cerebral palsy (CP), with verification by electrical stimulation.Method: A prospective observational study was performed in 75 children with spastic CP who received regular BoNT-A treatment under general anaesthesia (52 males, 23 females; mean age 8y 9mo, SD 3y 7mo, range 4-18y; mean body mass index 16.2, SD 3.7, range 7.7-26.7). A total of 1084 intramuscular needle placements using passive muscle stretching and relaxing were verified by electrical stimulation. Primary outcome was the positive predictive value.Results: Intramuscular needle placement in the muscles adductor brevis, adductor longus, gracilis, semimembranosus, semitendinosus, biceps femoris, rectus femoris, and lateral and medial heads of the gastrocnemius and soleus had a positive predictive value ranging from 85.7% to 100% (95% confidence interval ranging from 71.5-89.9% to 91.4-100%).Interpretation: This validated detailed protocol for intramuscular needle placement using passive muscle stretching and relaxing for BoNT-A treatment in the lower extremity of children with spastic CP is reliable and has a high positive predictive value. [ABSTRACT FROM AUTHOR]- Published
- 2016
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18. A randomized controlled trial of web-based training to increase activity in children with cerebral palsy.
- Author
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Mitchell, Louise E, Ziviani, Jenny, and Boyd, Roslyn N
- Subjects
CHILDREN with cerebral palsy ,ONLINE education ,WALKING ,PHYSICAL fitness ,PHYSICAL activity ,RANDOMIZED controlled trials ,CEREBRAL dominance ,CEREBRAL palsy ,COMPARATIVE studies ,EXERCISE therapy ,LONGITUDINAL method ,RESEARCH methodology ,MEDICAL cooperation ,MOTOR ability ,NONPARAMETRIC statistics ,ONLINE information services ,RESEARCH ,EVALUATION research ,ACCELEROMETRY ,TREATMENT effectiveness ,CASE-control method - Abstract
Aim: To determine the efficacy of web-based training on activity capacity and performance in children with unilateral cerebral palsy (CP).Method: In a matched-pairs randomized waitlist controlled trial, independently ambulant children and adolescents with unilateral CP were allocated to receive 30 minutes of training (intervention) 6 days per week, or usual care (waitlist control) for 20 weeks. Activity capacity was assessed using maximal repetitions of functional strength tasks and 6-minute walk test (6MWT); performance using 4-day ActiGraph GT3X+ accelerometer records at baseline and 20 weeks. Data were analysed by intention to treat comparing between groups using hierarchical linear modelling.Results: Participants were n=101, 52 males, mean age 11 years 3 months (SD 2y 4mo). Intervention participants completed a mean 32.4 hours (SD 17.2) of training, associated with significant improvements in functional strength (mean difference 19.3 repetitions; 95% confidence interval [CI] 10.8-27.7; p<0.001) and 6MWT distance (mean difference 38.9m; 95% CI 12.3-51.9; p<0.001) compared with the control group at 20 weeks, although not activity performance (p>0.05).Interpretation: Training was effective at increasing functional strength and walking endurance in independently ambulant children with unilateral CP. This did not translate into improvements in activity performance. [ABSTRACT FROM AUTHOR]- Published
- 2016
- Full Text
- View/download PDF
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