1. Neurodevelopmental profiles of children with unilateral cerebral palsy associated with middle cerebral artery and periventricular venous infarctions
- Author
-
Jan Willem Gorter, Darcy Fehlings, Gabrielle deVeber, Marie Kim, Carolyn Hunt, Anna McCormick, Ronit Mesterman, Renee-Marie Ragguett, and Pradeep Krishnan
- Subjects
Male ,030506 rehabilitation ,Adolescent ,Neuroimaging ,Cerebral palsy ,03 medical and health sciences ,0302 clinical medicine ,Developmental Neuroscience ,Interquartile range ,medicine.artery ,medicine ,Humans ,Child ,Intelligence quotient ,business.industry ,Cerebral Palsy ,Brain ,Infarction, Middle Cerebral Artery ,Gross Motor Function Classification System ,Original Articles ,Odds ratio ,medicine.disease ,Confidence interval ,Exact test ,Cross-Sectional Studies ,Motor Skills ,Child, Preschool ,Anesthesia ,Pediatrics, Perinatology and Child Health ,Middle cerebral artery ,Original Article ,Female ,Neurology (clinical) ,0305 other medical science ,business ,030217 neurology & neurosurgery - Abstract
Aim To compare the neurodevelopment of children with unilateral cerebral palsy (CP) with middle cerebral artery (MCA) and periventricular venous infarctions (PVIs). Method In this cross‐sectional study, children with unilateral CP completed a neurological exam, unimanual Quality of Upper Extremity Skills Test, hand usage questionnaires, and IQ test. Neuroimaging was obtained from health records. Results Two hundred and forty‐five participants with unilateral CP had neuroimaging (151 [61.9%] male, ages 2–18y, median=7y 6mo, interquartile range [IQR]=6y 7mo, with 93.6% in Gross Motor Function Classification System level I/II and 78.8% in Manual Ability Classification System level I/II). Ninety‐seven (39.6%) had MCA injuries and 106 (43.3%) had periventricular white matter injuries, of which 48 (45.3%) were PVIs. Median Quality of Upper Extremity Skills Test for the MCA group was 49.2 (IQR=55.8), PVI 79.9 (IQR=23.6) (Mann–Whitney U=988.50, p, Video Podcast: https://youtu.be/79w_s82qhr0
- Published
- 2021
- Full Text
- View/download PDF