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Start Over Author "St-Onge, Judith" Journal diabetes care
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2. Additive Effects of Obesity and TCF7L2 Variants on Risk for Type 2 Diabetes Among Cardiac Patients.

Author

Qing Ling Duan, Dubé, Marie-Pierre, Frasure-Smith, Nancy, Barhdadi, Amina, Lesperance, François, Théroux, Pierre, St-Onge, Judith, Rouleau, Guy A., and McCaffery, Jeanne M.

Subjects
TYPE 2 diabetes diagnosis, CARDIAC patients, OBESITY, TRANSCRIPTION factors, OVERWEIGHT persons
Abstract

The article focuses on a study on the combined effect of obesity and transcription factor 7-like 2 (TCF7L2) gene in predicting type 2 diabetes risk in cardiac patients. Results of the study showed the highest risk for type 2 diabetes was observed among obese individuals who carried at least one risk allele. The study found that the genetic association was stronger in nonobese patients. An interaction between obesity and genotype was not detected.

Published
2007
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