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Abstract: The current study aimed to evaluate whether individuals with fasting plasma glucose (FPG) of 5.6–6.0mmol/l has a similar risk profiles for diabetes or impaired glucose tolerance (IGT) to those with FPG of 6.1–6.9mmol/l. A community-based cross-sectional survey in Chinese adults (20–74 years) was conducted during April–July in 2002. Participants without a prior history of diabetes underwent a standardized 2-h 75g oral glucose tolerance test. Positive likelihood ratios were calculated to estimate the odds of having diabetes or IGT for subjects with different FPG levels. Among 1856 participants, prevalence of IFG increased from 12.4 to 28.2% with the cut-off value of FPG lowered from 6.1 to 5.6mmol/l. Individuals with FPG of 6.1–6.9mmol/l were more obese and insulin resistant than those with FPG of 5.6–6.0mmol/l. The positive likelihood ratio for diabetes and IGT were 1.83 (1.28–2.61) and 2.60 (1.96–3.44) in subjects with FPG of 6.1–6.9mmol/l, and 0.54 (0.30–0.95) and 1.47 (1.11–1.95) for those with FPG of 5.6–6.0mmol/l, respectively. In conclusion, the likelihood of diabetes and IGT was lower in subjects with FPG of 5.6–6.0mmol/l than in those with FPG of 6.1–6.9mmol/l. The clinical and social implication of labelling more individuals with impaired fasting glucose needs to be further studied. [Copyright &y& Elsevier]

Abstract: Objective: To investigate the association of fresh vegetable consumption with the risk of diabetes in a Chinese population. Methods: Data from 2386 individuals aged 35–74 years who participated in a population-based cross sectional diabetes survey in Qingdao, China were analyzed. Frequency of vegetable intake was obtained using a food frequency questionnaire. Diabetes was defined as self-reported diabetes or undiagnosed diabetes determined by 2-h 75g oral glucose tolerance test or fasting capillary blood glucose test. Multivariate-adjusted odds ratio (OR) for the presence (vs. the absence) of diabetes in association with the frequency of fresh vegetable intake was estimated using logistic regression analysis. Results: The OR for the presence of diabetes was 1.17 (95% CI 0.66, 2.05) in men and 0.50 (95% CI 0.33, 0.77) in women who ate fresh vegetables more than 14 times/week as compared with those who ate fresh vegetables less than 7 times/week after adjustment for age, family history of diabetes, BMI, systolic blood pressure, 24-h energy intake, physical activity and smoking and drinking. Conclusions: Consumption of fresh vegetables was associated with a low risk of having diabetes in women but not in men in this Chinese population. [Copyright &y& Elsevier]

Abstract: Objective: Serum uric acid (UA) is reported as an important marker of hypertension, coronary heart disease, and diabetes; diabetic subjects have low UA levels. The relationship between UA and fasting plasma glucose (FPG) and 2-h plasma glucose concentrations in non-diabetic subjects as well as in diabetic subjects in general population is not well known. This was investigated in a general Chinese population. Methods: A stratified, random cluster sampling method was performed to select a representative sample of general population aged 20–74 years in Qingdao in 2002. A total of 1288 men and 2344 women participated in the survey. The mean UA concentration was calculated for small glucose intervals and the trend was tested using general linear model. Results: The mean concentrations of UA were 381, 393, 371, and 345μmol/l in men with FPG of <6.1, 6.1–6.9, ≥7.0mmol/l (newly diagnosed diabetes), and in those with prior history of diabetes. They were 308, 322, 301, and 293μmol/l, respectively, in women. The UA levels declined with increasing FPG levels in individuals with newly diagnosed diabetes, with standardized coefficient of −0.26 in men and −0.20 in women, after multivariate adjustment for age, body mass index, triglycerides, and cardiovascular disease history. The relationship between 2-h glucose and UA was not as clear as that for FPG. Conclusion: Serum UA levels tended to increase with increasing FPG levels in non-diabetic individuals, but decrease in diabetic individuals. [Copyright &y& Elsevier]