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Your search keyword '"DAGNELIE, PIETER C."' showing total 10 results
Start Over Author "DAGNELIE, PIETER C." Journal diabetologia
10 results on '"DAGNELIE, PIETER C."'

1. (Pre)diabetes and a higher level of glycaemic measures are continuously associated with corneal neurodegeneration assessed by corneal confocal microscopy: the Maastricht Study

Author

Mokhtar, Sara B. A., primary, van der Heide, Frank C. T., additional, Oyaert, Karel A. M., additional, van der Kallen, Carla J. H., additional, Berendschot, Tos T. J. M., additional, Scarpa, Fabio, additional, Colonna, Alessia, additional, de Galan, Bastiaan E., additional, van Greevenbroek, Marleen M. J., additional, Dagnelie, Pieter C., additional, Schalkwijk, Casper G., additional, Nuijts, Rudy M. M. A., additional, Schaper, Nicolaas C., additional, Kroon, Abraham A., additional, Schram, Miranda T., additional, Webers, Carroll A. B., additional, and Stehouwer, Coen D. A., additional

Published
2023
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2. Sex differences in body composition in people with prediabetes and type 2 diabetes as compared with people with normal glucose metabolism: the Maastricht Study

Author

de Ritter, Rianneke, primary, Sep, Simone J. S., additional, van Greevenbroek, Marleen M. J., additional, Kusters, Yvo H. A. M., additional, Vos, Rimke C., additional, Bots, Michiel L., additional, Kooi, M. Eline, additional, Dagnelie, Pieter C., additional, Eussen, Simone J. P. M., additional, Schram, Miranda T., additional, Koster, Annemarie, additional, Brouwers, Martijn C. G., additional, van der Sangen, Niels M. R., additional, Peters, Sanne A. E., additional, van der Kallen, Carla J. H., additional, and Stehouwer, Coen D. A., additional

Published
2023
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3. Sedentary behaviour and physical activity are associated with biomarkers of endothelial dysfunction and low-grade inflammation—relevance for (pre)diabetes: The Maastricht Study

Author

Vandercappellen, Evelien J., primary, Koster, Annemarie, additional, Savelberg, Hans H. C. M., additional, Eussen, Simone J. P. M., additional, Dagnelie, Pieter C., additional, Schaper, Nicolaas C., additional, Schram, Miranda T., additional, van der Kallen, Carla J. H., additional, van Greevenbroek, Marleen M. J., additional, Wesselius, Anke, additional, Schalkwijk, Casper G., additional, Kroon, Abraham A., additional, Henry, Ronald M. A., additional, and Stehouwer, Coen D. A., additional

Published
2022
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4. Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study

Author

Bakker, Lieke, primary, Ramakers, Inez H. G. B., additional, van Boxtel, Martin P. J., additional, Schram, Miranda T., additional, Stehouwer, Coen D. A., additional, van der Kallen, Carla J. H., additional, Dagnelie, Pieter C., additional, van Greevenbroek, Marleen M. J., additional, Wesselius, Anke, additional, Midttun, Øivind, additional, Ueland, Per M., additional, Verhey, Frans R. J., additional, Eussen, Simone J. P. M., additional, and Köhler, Sebastian, additional

Published
2021
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5. Greater daily glucose variability and lower time in range assessed with continuous glucose monitoring are associated with greater aortic stiffness: The Maastricht Study

Author

Foreman, Yuri D., primary, van Doorn, William P. T. M., additional, Schaper, Nicolaas C., additional, van Greevenbroek, Marleen M. J., additional, van der Kallen, Carla J. H., additional, Henry, Ronald M. A., additional, Koster, Annemarie, additional, Eussen, Simone J. P. M., additional, Wesselius, Anke, additional, Reesink, Koen D., additional, Schram, Miranda T., additional, Dagnelie, Pieter C., additional, Kroon, Abraham A., additional, Brouwers, Martijn C. G. J., additional, and Stehouwer, Coen D. A., additional

Published
2021
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6. The association of hyperglycaemia and insulin resistance with incident depressive symptoms over 4 years of follow-up: The Maastricht Study

Author

Geraets, Anouk F. J., primary, Köhler, Sebastian, additional, Muzambi, Rutendo, additional, Schalkwijk, Casper G., additional, Oenema, Anke, additional, Eussen, Simone J. P. M., additional, Dagnelie, Pieter C., additional, Stehouwer, Coen D. A., additional, Schaper, Nicolaas C., additional, Henry, Ronald M. A., additional, van der Kallen, Carla J. H., additional, Wesselius, Anke, additional, Koster, Annemarie, additional, Verhey, Frans R. J., additional, and Schram, Miranda T., additional

Published
2020
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7. Which is more important for cardiometabolic health: sedentary time, higher intensity physical activity or cardiorespiratory fitness? The Maastricht Study

Author

van der Velde, Jeroen H. P. M., primary, Schaper, Nicolaas C., additional, Stehouwer, Coen D. A., additional, van der Kallen, Carla J. H., additional, Sep, Simone J. S., additional, Schram, Miranda T., additional, Henry, Ronald M. A., additional, Dagnelie, Pieter C., additional, Eussen, Simone J. P. M., additional, van Dongen, Martien C. J. M., additional, Savelberg, Hans H. C. M., additional, and Koster, Annemarie, additional

Published
2018
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8. Discriminatory ability of simple OGTT-based beta cell function indices for prediction of prediabetes and type 2 diabetes: the CODAM study

Author

den Biggelaar, Louise J. C. J., primary, Sep, Simone J. S., additional, Eussen, Simone J. P. M., additional, Mari, Andrea, additional, Ferrannini, Ele, additional, van Greevenbroek, Marleen M. J., additional, van der Kallen, Carla J. H., additional, Schalkwijk, Casper G., additional, Stehouwer, Coen D. A., additional, and Dagnelie, Pieter C., additional

Published
2016
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9. Associations of total amount and patterns of sedentary behaviour with type 2 diabetes and the metabolic syndrome: The Maastricht Study

Author

van der Berg, Julianne D., primary, Stehouwer, Coen D. A., additional, Bosma, Hans, additional, van der Velde, Jeroen H. P. M., additional, Willems, Paul J. B., additional, Savelberg, Hans H. C. M., additional, Schram, Miranda T., additional, Sep, Simone J. S., additional, van der Kallen, Carla J. H., additional, Henry, Ronald M. A., additional, Dagnelie, Pieter C., additional, Schaper, Nicolaas C., additional, and Koster, Annemarie, additional

Published
2016
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10. Discriminatory ability of simple OGTT-based beta cell function indices for prediction of prediabetes and type 2 diabetes: the CODAM study.

Author

den Biggelaar LJ, Sep SJ, Eussen SJ, Mari A, Ferrannini E, van Greevenbroek MM, van der Kallen CJ, Schalkwijk CG, Stehouwer CD, and Dagnelie PC

Subjects
Aged, Blood Glucose metabolism, Body Mass Index, Diabetes Mellitus, Type 2 blood, Female, Humans, Insulin metabolism, Male, Middle Aged, Prediabetic State blood, ROC Curve, Diabetes Mellitus, Type 2 diagnosis, Glucose Tolerance Test methods, Insulin-Secreting Cells physiology, Prediabetic State diagnosis
Abstract

Aims/hypothesis: The hyperglycaemic clamp technique and the frequently sampled IVGTT are unsuitable techniques to assess beta cell function (BCF) in large cohorts. Therefore, the aim of this study was to evaluate the discriminatory ability of simple OGTT-based BCF indices for prediction of prediabetes (meaning impaired fasting glucose and/or impaired glucose tolerance) and type 2 diabetes., Methods: Glucose metabolism status was assessed by 2 h 75 g OGTT at baseline (n = 476, mean age 59.2 years, 38.7% women) and after 7 years of follow-up (n = 416) in the Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) study (1999-2009). Baseline plasma glucose, insulin and C-peptide values during OGTTs were used to calculate 21 simple indices of BCF. Disposition indices (BCF index × Matsuda index), to compensate for the prevailing level of insulin resistance, were calculated for the BCF indices with the best discriminatory abilities. The discriminatory ability of the BCF indices was estimated by the area under the receiver operating characteristics curve (ROC AUC) with an outcome of incident prediabetes (n = 73) or type 2 diabetes (n = 60 and n = 18 cases, respectively, in individuals who were non-diabetic or had normal glucose metabolism at baseline)., Results: For incident prediabetes (n = 73), all ROC AUCs were less than 70%, whereas for incident type 2 diabetes, I 30 /I 0 , CP 30 /CP 0 , ΔI 30 /ΔG 30 , ΔCP 30 /ΔG 30 (where I, CP and G are the plasma concentrations of insulin, C-peptide and glucose, respectively, at the times indicated), and corrected insulin response at 30 min had ROC AUCs over 70%. In at-baseline non-diabetic individuals, disposition indices ΔI 30 /ΔG 30 , ΔCP 30 /ΔG 30 and corrected insulin response at 30 min had ROC AUCs of over 80% for incident type 2 diabetes. Moreover, these BCF disposition indices had significantly better discriminatory abilities for incident type 2 diabetes than the Matsuda index alone., Conclusions/interpretation: BCF indices reflecting early-phase insulin secretion have the best ability to discriminate individuals who will develop prediabetes and type 2 diabetes. Of these, ΔCP 30 /ΔG 30 , often referred to as the C-peptidogenic index, performed consistently well.

Published
2017
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