1. Primary follicular dendritic cell sarcoma of the urinary bladder: the first case report and potential diagnostic pitfalls
- Author
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You-Li Wu, Lang Lang, Zhi-Wen Chen, Xiao-Chu Yan, Guangjie Duan, and Hui Sun
- Subjects
0301 basic medicine ,Pathology ,Lung Neoplasms ,Time Factors ,medicine.medical_treatment ,Biopsy ,Case Report ,Cryosurgery ,Metastasis ,0302 clinical medicine ,Ultrasonography, Doppler, Color ,Pneumonectomy ,Urinary bladder ,General Medicine ,Middle Aged ,Immunohistochemistry ,medicine.anatomical_structure ,Treatment Outcome ,030220 oncology & carcinogenesis ,Female ,lcsh:RB1-214 ,medicine.medical_specialty ,Histology ,Dendritic Cell Sarcoma, Follicular ,Malignancy ,Cystectomy ,Pathology and Forensic Medicine ,Diagnosis, Differential ,03 medical and health sciences ,Predictive Value of Tests ,Bronchoscopy ,medicine ,Carcinoma ,lcsh:Pathology ,Biomarkers, Tumor ,Humans ,Bladder cancer ,business.industry ,medicine.disease ,Radiation therapy ,Treatment ,030104 developmental biology ,Urinary Bladder Neoplasms ,Follicular dendritic cell sarcoma ,Diagnostic pitfall ,Radiotherapy, Adjuvant ,business ,Tomography, X-Ray Computed - Abstract
Background Extranodal follicular dendritic cell sarcoma (FDCS) is a very rare malignancy with a variable clinical course. It is often not considered and has the potential to result in a misdiagnosis of other common sarcomas or sarcomatoid carcinomas. This is particularly true with the preoperative biopsy specimen, in which the tissue sample is often small. Case presentation A case of FDCS in a 63-year-old woman, arising in the urinary bladder, a previously unreported site, is described. The patient presented with the typical clinical symptoms of a bladder cancer, and the morphology of the tumor was similar to a lymphoepithelioma-like carcinoma, ultimately resulting in it being misdiagnosed. The patient received radical cystectomy, without further radiotherapy or chemotherapy. Two years after operation, a metastatic tumor to the lung was found. The mass of the right main bronchus lumen was frozen and resected through bronchoscopy, and radiotherapy was performed. The patient has lived with the tumor since then. Conclusions This paper presents the first FDCS occurring in the urinary bladder with metastasis to the lung and emphasizes potential diagnostic pitfalls.
- Published
- 2016