Search

Your search keyword '"Akizue N"' showing total 2 results
Start Over Author "Akizue N" Journal digestion
2 results on '"Akizue N"'

1. Clinical Features Focusing on Extraintestinal Manifestations in Japanese Patients with Inflammatory Bowel Diseases: Far East 1000.

Author

Ohta Y, Taida T, Kato J, Ogasawara S, Oyama Y, Mamiya Y, Nakazawa H, Horio R, Goto C, Takahashi S, Kurosugi A, Sonoda M, Shiratori W, Kaneko T, Yokoyama Y, Akizue N, Ishigami H, Koseki H, Okimoto K, Saito K, Saito M, Matsumura T, Nakagawa T, Masuya Y, Fukuda Y, Kitsukawa Y, Shimura H, Tsuyuguchi T, and Kato N

Subjects
Humans, East Asian People, Quality of Life, Arthritis epidemiology, Arthritis etiology, Colitis, Ulcerative complications, Colitis, Ulcerative epidemiology, Crohn Disease complications, Crohn Disease epidemiology, Inflammatory Bowel Diseases complications, Inflammatory Bowel Diseases epidemiology, Joint Diseases etiology, Joint Diseases complications
Abstract

Background: Patients with inflammatory bowel diseases (IBD) can develop extraintestinal manifestations (EIMs) during the disease course, which sometimes impact their quality of life., Objectives: This study aimed to clarify the prevalence and types of EIMs using a hospital-based IBD cohort in Japan., Methods: A patient cohort with IBD was established in 2019, as participated by 15 hospitals in Chiba Prefecture of Japan. Using this cohort, the prevalence and types of EIMs, which are defined based on previous reports and the Japanese guidelines, were investigated., Results: This cohort enrolled 728 patients, including 542 ulcerative colitis (UC) and 186 Crohn's disease (CD). Of these patients with IBD, 10.0% were identified with one or more EIMs (57 (10.5%) with UC and 16 (8.6%) with CD). Arthropathy and arthritis were the most common EIM in 23 (4.2%) patients with UC, followed by primary sclerosing cholangitis (PSC) (2.6%). Arthropathy and arthritis were also the most common in patients with CD, but no cases of PSC were observed. EIMs were more frequently observed in patients with IBD treated by specialists than in those treated by non-specialists (12.7% vs. 5.5%, p = 0.011). The incidence of EIMs in patients with IBD was not significantly different over time., Conclusions: The prevalence and types of EIMs in our hospital-based cohort in Japan did not significantly differ from those reported in previous or Western studies. However, the incidence might be underestimated due to the limited ability of non-IBD specialists to discover and describe EIMs in patients with IBD., (© 2023 S. Karger AG, Basel.)

Published
2023
Full Text
View/download PDF

2. Evaluation of Esophageal Mucosal Integrity in Patients with Gastroesophageal Reflux Disease.

Author

Matsumura T, Arai M, Ishigami H, Fujie M, Ishikawa K, Akizue N, Taida T, Ohta Y, Hamanaka S, Okimoto K, Saito K, Maruoka D, Nakagawa T, and Kato N

Subjects
Catheters, Esophageal Mucosa pathology, Esophageal pH Monitoring, Esophagoscopes, Esophagoscopy instrumentation, Gastroesophageal Reflux pathology, Humans, Hydrogen-Ion Concentration, Monitoring, Physiologic adverse effects, Monitoring, Physiologic methods, Time Factors, Electric Impedance, Esophageal Mucosa diagnostic imaging, Esophagoscopy methods, Gastroesophageal Reflux diagnostic imaging
Abstract

Background: Impaired esophageal mucosal integrity plays a role in causing symptoms of gastroesophageal reflux disease (GERD). Recently, the assessment of esophageal baseline impedance (BI) using the multichannel intraluminal impedance-pH (MII-pH) test was suggested as a surrogate technique for the study of esophageal mucosal integrity and was reported to be useful in distinguishing GERD from non-GERD. However, measuring BI requires a 24-h testing period, is complicated, and causes considerable patient discomfort., Summary: Recently, endoscopy-guided catheters that can measure mucosal impedance (MI) and mucosal admittance (MA), which is the inverse of impedance, were developed, and their usefulness in measuring MI and MA for the diagnosis of GERD has been reported. In these studies, esophageal MI values were significantly lower in patients with GERD than in those without GERD. In contrast, esophageal MA was significantly higher in patients with GERD than in those without. Furthermore, we reported that MA is inversely correlated with BI and correlated with acid exposure time. Key Messages: Endoscopy-guided real-time measurement of MI and MA may allow the estimation of mucosal integrity and may be a useful diagnostic tool for patients with GERD in a manner similar to 24-h MII-pH monitoring., (© 2018 S. Karger AG, Basel.)

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results