1. Effects of experimental gastroduodenal reflux on density of mast cells and plasmocytes in the fundic mucosa of the rat
- Author
-
H. Slaoui, Sylvie Cavagna, Claude André, and Françoise André
- Subjects
Male ,medicine.medical_specialty ,Pathology ,Plasma Cells ,Immunoglobulins ,Immunoglobulin E ,Gastroenterology ,Duodenogastric Reflux ,Bile reflux ,Internal medicine ,Gastric mucosa ,Medicine ,Animals ,Mast Cells ,Gastritis, Hypertrophic ,biology ,business.industry ,Rats, Inbred Strains ,Hyperplasia ,medicine.disease ,Mast cell ,digestive system diseases ,Rats ,medicine.anatomical_structure ,Gastric Mucosa ,biology.protein ,Female ,Gastritis ,medicine.symptom ,Antibody ,business - Abstract
IgA-, IgM-, IgG- and IgE-positive plasmocytes and mast cells were counted in the fundic mucosa of two groups of rats which underwent gastroenteroanastomosis or sham operation 12 months previously. Experimentally induced duodenogastric reflux constitutes a model for biliary gastritis which is characterized by a decrease in the IgA plasmocyte count along with an increase in IgG and IgE plasmocytes and, especially, an increase in mast cells. It is suggested that this allergic-type reaction is responsible for the hyperplasia of gastric crypts seen in biliary gastritis.
- Published
- 1987