5 results on '"Lupo, Luigi"'
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2. Temporal trends of waitlistings for liver transplantation in Italy: The ECALITA (Evolution of IndiCAtion in LIver transplantation in ITAly) registry study
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Manzia, Tommaso Maria, Trapani, Silvia, Nardi, Alessandra, Ricci, Andrea, Lenci, Ilaria, Milana, Martina, Angelico, Roberta, De Feo, Tullia Maria, Agnes, Salvatore, Andorno, Enzo, Baccarani, Umberto, Carraro, Amedeo, Cescon, Matteo, Cillo, Umberto, Colledan, Michele, De Carlis, Luciano, De Simone, Paolo, Di Benedetto, Fabrizio, Ettorre, Giuseppe Maria, Gruttadauria, Salvatore, Lupo, Luigi Giovanni, Mazzaferro, Vincenzo, Romagnoli, Renato, Rossi, Giorgio, Rossi, Massimo, Spada, Marco, Vennarecci, Giovanni, Vivarelli, Marco, Zamboni, Fausto, Tisone, Giuseppe, Cardillo, Massimo, and Angelico, Mario
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- 2022
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3. Liver Match, a prospective observational cohort study on liver transplantation in Italy: Study design and current practice of donor–recipient matching
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Angelico, Mario, Cillo, Umberto, Fagiuoli, Stefano, Gasbarrini, Antonio, Gavrila, Caius, Marianelli, Tania, Costa, Alessandro Nanni, Nardi, Alessandra, Strazzabosco, Mario, Burra, Patrizia, Agnes, Salvatore, Baccarani, Umberto, Calise, Fulvio, Colledan, Michele, Cuomo, Oreste, De Carlis, Luciano, Donataccio, Matteo, Ettorre, Giuseppe M., Gerunda, Giorgio E., Gridelli, Bruno, Lupo, Luigi, Mazzaferro, Vincenzo, Pinna, Antonio, Risaliti, Andrea, Salizzoni, Mauro, Tisone, Giuseppe, Valente, Umberto, Rossi, Giorgio, Rossi, Massimo, and Zamboni, Fausto
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- 2011
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4. Effect of direct-acting antivirals on future occurrence of hepatocellular carcinoma in compensated cirrhotic patients
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Cucchetti, Alessandro, D’Amico, Gennaro, Trevisani, Franco, Morelli, Maria Cristina, Vitale, Alessandro, Pinna, Antonio Daniele, Cescon, Matteo, Cillo, Umberto, Burra, Patrizia, Russo, Francesco P., Mescoli, Claudia, Rendina, Maria, Lupo, Luigi G., Losito, Francesco, Fucilli, Fabio, Brancaccio, Giusep-Pina, Persico, Marcello, Viganò, Luca, Iavarone, Massimo, D’Ambrosio, Roberta, Sangiovanni, Angelo, Renzulli, Matteo, Galati, Giovanni, Ponziani, Francesca Romana, Pompili, Maurizio, Miele, Luca, Grieco, Antonio, Rapaccini, Gianlodovico, Gasbarrini, Antonio, Sandri, Giovanni Battisa Levi, Lai, Quirino, Melandro, Fabio, Rossi, Massimo, Lenci, Ilaria, Manzia, Tommaso Maria, Tortora, Raffaella, Di Costanzo, Giovan Giuseppe, Sacco, Rodolfo, Simonetti, Natalia, Morisco, Filomena, Guarino, Maria, Cabibbo, Giuseppe, Bhoori, Carlo Sposito Sherrie, Di Sandro, Stefano, Foschi, Francesco Giuseppe, Gardini, Andrea Casadei, Nicolini, Daniele, Mazzocato, Susanna, Alba, Kostandini, Violi, Paola, Baccarani, Umberto, Pravisani, Riccardo, A. Cucchetti, G. D'Amico, F. Trevisani, M.C. Morelli, A. Vitale, A.D.Pinna, M. Cescon, Cucchetti, Alessandro, D’Amico, Gennaro, Trevisani, Franco, Morelli, Maria Cristina, Vitale, Alessandro, Pinna, Antonio Daniele, Cescon, Matteo, Cillo, Umberto, Burra, Patrizia, Russo, Francesco P., Mescoli, Claudia, Rendina, Maria, Lupo, Luigi G., Losito, Francesco, Fucilli, Fabio, Brancaccio, Giusep-Pina, Persico, Marcello, Viganò, Luca, Iavarone, Massimo, D’Ambrosio, Roberta, Sangiovanni, Angelo, Renzulli, Matteo, Galati, Giovanni, Ponziani, Francesca Romana, Pompili, Maurizio, Miele, Luca, Grieco, Antonio, Rapaccini, Gianlodovico, Gasbarrini, Antonio, Sandri, Giovanni Battisa Levi, Lai, Quirino, Melandro, Fabio, Rossi, Massimo, Lenci, Ilaria, Manzia, Tommaso Maria, Tortora, Raffaella, Di Costanzo, Giovan Giuseppe, Sacco, Rodolfo, Simonetti, Natalia, Morisco, Filomena, Guarino, Maria, Cabibbo, Giuseppe, Bhoori, Carlo Sposito Sherrie, Di Sandro, Stefano, Foschi, Francesco Giuseppe, Gardini, Andrea Casadei, Nicolini, Daniele, Mazzocato, Susanna, Alba, Kostandini, Violi, Paola, Baccarani, Umberto, and Pravisani, Riccardo
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Male ,Time Factors ,Sustained Virologic Response ,Hepatocellular carcinoma ,Hepacivirus ,Direct-acting antiviral ,Direct-acting antivirals ,medicine.disease_cause ,Gastroenterology ,Competing risk ,Hepatitis C ,Markov model ,Survival benefit ,Sustained virological response ,Hepatology ,0302 clinical medicine ,Risk Factors ,030212 general & internal medicine ,biology ,Incidence ,Incidence (epidemiology) ,Liver Neoplasms ,Middle Aged ,Markov Chains ,Competing risk Direct-acting antivirals Hepatitis C Hepatocellular carcinoma Markov model Survival benefit Sustained virological response ,Italy ,Liver Neoplasm ,Female ,030211 gastroenterology & hepatology ,Human ,Adult ,medicine.medical_specialty ,Carcinoma, Hepatocellular ,Time Factor ,Hepatitis C virus ,Antiviral Agents ,03 medical and health sciences ,Internal medicine ,medicine ,Humans ,Antiviral Agent ,Hepaciviru ,business.industry ,Risk Factor ,Carcinoma ,Hepatocellular ,Markov Chain ,medicine.disease ,biology.organism_classification ,digestive system diseases ,Settore MED/18 - Chirurgia Generale ,Liver function ,Varices ,business - Abstract
Background: The achievement of high rates of sustained virological response (SVR) with direct-acting antivirals (DAAs) in hepatitis C virus (HCV) infected patients will reduce decompensating terminal events. Aims: To investigate whether hepatocellular carcinoma (HCC) occurrence could change due to the DAA-induced increase in life-expectancy. Methods: A Markov model was built on clinical data of 494 cirrhotic patients and available literature to estimate probabilities of “death before HCC” and of “HCC occurrence” without and with DAA. Results: In comparison to untreated patients, DAA therapy reduced the 20-year mortality before HCC by 21.9% in patients without varices and by 21.5% in those with varices, considering an SVR of 95% and no direct effect on hepatocarcinogenesis. Tumour occurrence increased by 5%–8.2% and the proportion of HCCs diagnosed in compensated stages increased to >98%. If we consider DAA as having “anti-tumoral” effects, the benefit becomes greater, achieving a 20-year survival of 81.5% in patients without varices, and 52.2% in patients with varices. Instead, if we consider DAA as having a “pro-tumoral” effect, then, the increased incidence of HCC nullifies the survival benefits. Conclusion: DAAs drastically reduce the mortality caused by the liver function worsening, increasing the proportion of HCCs diagnosed in compensated stages. Knowledge of the DAA effect on hepatocarcinogenesis remains pivotal. © 2017 Editrice Gastroenterologica Italiana S.r.l.
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- 2018
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5. Recurrence of hepatocellular carcinoma after direct acting antiviral treatment for hepatitis C virus infection: Literature review and risk analysis
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Guarino, Maria, primary, Viganò, Luca, additional, Ponziani, Francesca Romana, additional, Giannini, Edoardo Giovanni, additional, Lai, Quirino, additional, Morisco, Filomena, additional, Vitale, Alessandro, additional, Russo, Francesco Paolo, additional, Cillo, Umberto, additional, Burra, Patrizia, additional, Mescoli, Claudia, additional, Gambato, Martina, additional, Sessa, Anna, additional, Cabibbo, Giuseppe, additional, Viganò, Mauro, additional, Galati, Giovanni, additional, Villa, Erica, additional, Iavarone, Massimo, additional, Brancaccio, Giuseppina, additional, Rendina, Maria, additional, Lupo, Luigi G., additional, Losito, Francesco, additional, Fucilli, Fabio, additional, Persico, Marcello, additional, D’Ambrosio, Roberta, additional, Sangiovanni, Angelo, additional, Cucchetti, Alessandro, additional, Trevisani e Matteo Renzulli, Franco, additional, Miele, Luca, additional, Grieco, Antonio, additional, Lodovico Rapaccini, Gian, additional, Pompili, Maurizio, additional, Gasbarrini, Antonio, additional, Battista Levi Sandri, Giovanni, additional, Melandro, Fabio, additional, Rossi, Massimo, additional, Lenci, Ilaria, additional, Manzia, Tommaso Maria, additional, Tortora, Raffaella, additional, Di Costanzo, Giovan Giuseppe, additional, Sacco, Rodolfo, additional, Ghinolfi, Davide, additional, Rreka, Erion, additional, Carrai, Paola, additional, Simonetti, Natalia, additional, Sposito, Carlo, additional, Bhoori, Sherrie, additional, di Sandro, Stefano, additional, Foschi, Francesco Giuseppe, additional, Casadei Gardini, Andrea, additional, Nicolini, Daniele, additional, Mazzocato, Susanna, additional, Kostandini, Alba, additional, Violi, Paola, additional, Baccarani, Umberto, additional, Pravisani, Riccardo, additional, and Vincenzi, Valter, additional
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- 2018
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