1. Perception of Illness and Its Association with Treatment Willingness in Patients with Newly Diagnosed Nonalcoholic Fatty Liver Disease
- Author
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Neerav Goyal, Abin M Abraham, Rajan Sharma, Pankaj Bansal, Rajat Soloman, Amandeep Goyal, Harpal S. Dhaliwal, and Ripudaman Singh
- Subjects
Adult ,Male ,Health Knowledge, Attitudes, Practice ,medicine.medical_specialty ,Psychometrics ,Physiology ,Population ,India ,Chronic liver disease ,03 medical and health sciences ,Liver disease ,0302 clinical medicine ,Cost of Illness ,Non-alcoholic Fatty Liver Disease ,Risk Factors ,Surveys and Questionnaires ,Internal medicine ,Nonalcoholic fatty liver disease ,medicine ,Humans ,Family history ,education ,Aged ,Illness Behavior ,education.field_of_study ,business.industry ,Public health ,Gastroenterology ,Middle Aged ,Patient Acceptance of Health Care ,medicine.disease ,Obesity ,Cross-Sectional Studies ,030220 oncology & carcinogenesis ,Population study ,Female ,030211 gastroenterology & hepatology ,Patient Participation ,business - Abstract
Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease of immense public health relevance. Understanding illness perceptions in the NAFLD population will provide sound scientific evidence for planning high-quality patient-centered care and implementing effective interventions. The Brief Illness Perception Questionnaire (BIPQ) is a robust psychometric tool to systematically assess the dimensions of illness perceptions in various chronic ailments. In a cross-sectional study enrolling patients with newly diagnosed NAFLD, the sociodemographic, anthropometric, biochemical, and radiological determinants of enhanced illness perceptions (measured by the BIPQ score) were investigated using univariate and multivariable binary logistic regression analyses. Finally, the association between individual domains of the BIPQ and willingness to participate in comprehensive medical management was explored. In total, 264 patients (mean age 53 ± 11.9 years, 59.8% males) were enrolled in the final analysis. The mean and median BIPQ scores in the study population were 30.3 ± 12.8 and 31.0 (IQR, 22.0–40.0), respectively. The variables having a significant independent association with heightened perceptions (BIPQ > 31) were family history of liver disease (aOR, 5.93; 95% CI, 1.42–24.74), obesity (aOR, 3.33; 95% CI, 1.57–7.05), diabetes mellitus (aOR, 2.35; 95% CI, 1.01–5.49), and transaminitis (aOR, 2.85; 95% CI, 1.42–5.69). Patients with a higher level of illness perceptions (31.6 ± 12.9 vs 27.8 ± 12.3, p = 0.022) were more likely to express a willingness to participate in the comprehensive management plan, with 3 of the 8 domains (consequence, identity, and treatment control) mainly affecting willingness. A family history of liver disease, obesity, diabetes, and transaminitis were independently associated with increased illness perceptions. A belief in serious consequences, a strong illness identity, and higher perceived treatment control were significantly associated with the willingness to undergo comprehensive care for NAFLD.
- Published
- 2021
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