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Objective To investigate whether six combined computer- and mobile-based physical activity interventions differ regarding use, attrition, usability and appreciation among adults aged 50 years and older. Methods The interventions were studied in a randomized controlled trial. Participants were allocated to the computer-based Active Plus or I Move program including a mobile-based activity tracker, or ecological momentary intervention (EMI), or chatbot, or to a waiting list control group. Use and attrition were investigated via log data gathered within the intervention software. Appreciation was assessed via online evaluation questionnaires. ANOVAs and Chi-squares were performed to test for intervention differences on use, attrition and appreciation ( p ≤ .05). Results A total of 954 participants aged 50 years and older with varying health conditions were included. Attrition differed between interventions ( χ 2 = 27.121, p