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Your search keyword '"Tamahkar, Emel"' showing total 2 results
Start Over Author "Tamahkar, Emel" Journal drug development research
2 results on '"Tamahkar, Emel"'

2. Evaluation of hyaluronic acid nanoparticle embedded chitosan–gelatin hydrogels for antibiotic release.

Author

Özkahraman, Bengi, Tamahkar, Emel, İdil, Neslihan, Kılıç Suloglu, Aysun, and Perçin, Işık

Subjects
*HYALURONIC acid, *DISC diffusion tests (Microbiology), *ANTIBIOTICS, *DRUG delivery systems, *GELATIN, *HYDROGELS, *CELL survival
Abstract

The development of chitosan–gelatin (CS‐G) hydrogels embedded with ampicillin‐loaded hyaluronic acid nanoparticles (HA‐NPs) for wound dressing is proposed. It was aimed to provide controlled ampicillin delivery by incorporation of HA‐NPs into biocompatible CS‐G hydrogel structure. According to in vitro ampicillin release studies, 55% of ampicillin was released from CS‐G/HA‐NPs hydrogels after 5 days. Antibacterial performance of CS‐G/HA‐NPs hydrogels was proven with agar disc diffusion test. For cytotoxicity assay, fibroblast cell viability increased in CS‐G/HA‐NPs hydrogels compared with CS‐G group after 24 hr incubation. Consequently, the potential ability of CS‐G/HA‐NPs hydrogels as a controlled drug delivery system has been verified. [ABSTRACT FROM AUTHOR]

Published
2021
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