1. Spare and repair the gut microbiota from antibiotic-induced dysbiosis: state-of-the-art.
- Author
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Andremont A, Cervesi J, Bandinelli PA, Vitry F, and de Gunzburg J
- Subjects
- Animals, Dysbiosis prevention & control, Humans, Anti-Bacterial Agents adverse effects, Dysbiosis chemically induced, Gastrointestinal Microbiome drug effects
- Abstract
Homeostasis of the intestinal microbiota is currently recognized as a major contributor to human health. Furthermore, intestinal dysbiosis is associated with a multitude of consequences, including intestinal colonization by antibiotic-resistant or pathogenic bacteria, such as Clostridioides difficile, and reduced efficacy of promising anticancer immunotherapies. By far, the most immediate and drastic exposure leading to dysbiosis is antibiotic treatment. Many attempts have been made to prevent or repair antibiotic-associated dysbiosis. Here, we review these innovations and the difficulties associated with their development., (Copyright © 2021 Elsevier Ltd. All rights reserved.)
- Published
- 2021
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