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By a News Reporter-Staff News Editor at Drug Week -- New research on Natural Product Chemistry is the subject of a report. According to news reporting out of Tempe, Arizona, [...]

'A series of alkylated (bis)urea and (bis)thiourea polyamine analogues were synthesized and screened for antimalarial activity against chloroquine-sensitive and -resistant strains of Plasmodium falciparum in vitro. All analogues showed growth [...]

According to the authors of recent research published in the journal Bioorganic & Medicinal Chemistry Letters, 'A series of rifamycin S and rifampin analogues incorporating substituted 8-amino, 8-thio, and 1,8-pyrazole [...]

'The synthesis of bis-steroidal pyrazines derived from 3-oxo-11,21-dihydroxypregna-4,17(20)-diene (4) and glycosylation of a D-ring side chain with alpha-L-rhamnose have been summarized. Rearrangement of steroidal pyrazine 10 to 14 was found [...]

Current study results from the report, 'Determination of azoles in sewage sludge from Spanish wastewater treatment plants by liquid chromatography-tandem mass spectrometry,' have been published. 'A simple and rapid analytical [...]

A report, 'Preparation of calibration standards of N1-H paralytic shellfish toxin analogues by large-scale culture of cyanobacterium Anabaena circinalis (TA04),' is newly published data in Marine Drugs. According to the [...]

A report, 'Kidney protection during peptide receptor radionuclide therapy with somatostatin analogues,' is newly published data in European Journal of Nuclear Medicine and Molecular Imaging. 'This review focuses on the [...]

'Curcumin (diferuloylmethane) is an orange-yellow compound from turmeric (Curcuma longa), a spice found in curry powder. Traditionally known for its anti-inflammatory effects, curcumin has established itself in the last two [...]

New research, 'Conformational analyses and MO studies of f152A1 and its analogues as potent protein kinase inhibitors,' is the subject of a report. 'f152A1 was isolated from a fermentation broth [...]

New research, 'Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues,' is the subject of a report. 'Based on recent reports that several (E)-8-styrylcaffeinyl analogues are potent reversible inhibitors of monoamine oxidase [...]

Fresh data on chymotrypsin are presented in the report 'Selection of peptomeric inhibitors of bovine alpha-chymotrypsin and cathepsin G based on trypsin inhibitor SFTI-1 using a combinatorial chemistry approach.' According [...]

According to a study from Montreal, Canada, 'In an effort to improve the bioavailability of the non-selective, cyclic enkephalin analogues H-Dmt-c[d-Cys-Gly-Phe-d(or L)-Cys]NH2 (Dmt = 2',6'-dimethyltyrosine), analogues N-methylated at the Phe4 [...]

Lipid analogues demonstrate a wide array of transfection capabilities. 'Inspired by the previously reported superior gene transfer efficacies of amine headgroup-containing cationic lipids to their hydroxy counterparts, in the present [...]