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1. Multidisciplinary approach to the therapy of chronic sinusitis.

Author

Bassetti D, Concia E, Solbiati M, and Sampietro M

Subjects
Adult, Aged, Cefotetan pharmacokinetics, Chronic Disease, Female, Humans, Male, Maxillary Sinus analysis, Middle Aged, Mucous Membrane analysis, Tissue Distribution, Cefotetan therapeutic use, Sinusitis drug therapy
Abstract

Twenty patients with maxillary sinusitis were treated with cefotetan (1 g, i.m.) twice a day. Samples of blood and maxillary sinus mucous membrane were taken in eight patients 2 h after dosing during the third day of therapy to evaluate drug concentration. Results show the excellent clinical and bacteriological effectiveness of cefotetan, as well as its high tissue penetration.

Published
1988

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