1. A new rhodamine-based fluorescent chemosensor for Fe3+ and its application in living cell imaging.
- Author
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Li, Chun-Yan, Zou, Chun-Xiang, Li, Yong-Fei, Tang, Jia-Liang, and Weng, Chao
- Subjects
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RHODAMINES , *FLUORESCENT dyes , *CHEMORECEPTORS , *IRON ions , *COLOR change sensors , *CELL imaging , *CHEMICAL synthesis - Abstract
Abstract: A new rhodamine-based compound (1) has been synthesized and applied as an “off–on” chemosensor for Fe3+. The comparison of this method with some other fluorescence methods for Fe3+ indicates that the method can detect Fe3+ in living cells by fluorescence enhancement and color changes with high sensitivity and selectivity. The fluorescence intensity of 1 is significantly increased about 60-fold with 20 equiv of Fe3+ added. Most importantly, the fluorescence changes of the chemosensor are remarkably specific for Fe3+ in the presence of other metal ions, which meet the selective requirements for practical application. Moreover, the experiment results show that the response behavior of 1 towards Fe3+ is pH independent in neutral condition (pH 6.0–8.0) and the response of the chemosensor is fast (response time less than 2 min). In addition, the proposed chemosensor has been used for imaging of Fe3+ in living cells with satisfying results. [Copyright &y& Elsevier]
- Published
- 2014
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