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Calcium carbonate is a chemical compound composed out of three elements; calcium, carbon and oxygen, and we can describe it with the chemical formula CaCO3. In natural form, it is found mostly in rocks in every part of the world, in shells of marine animals, snails, eggshells etc. Humans have used calcium carbonate since prehistory, and it is used today in various branches of human activity, including medicine and pharmacy. Calcium carbonate is nowadays used as a drug from a group of drugs that affect the alimentary tract and metabolism. It is used in the treatment of hyperacidity, heartburn and flatulence symptoms, as well as in the treatment of hyperphosphatemia in renal patients. It is also used in the form of a dietary supplement, most useful for calcium supplementation, in people with low levels of calcium or in people that are in the risk group. It is often found in food where it appears in the form of a food additive, where it serves as a dye, nutrient, acidity regulator. In addition, calcium carbonate is today widely used in the pharmaceutical industry as an adjuvant, enabling the formation of medicinal preparations. In this paper, the role of calcium carbonate in the preservation of human health and disease prevention will be elaborated through the presentation of its use in various preparations related to human health. [ABSTRACT FROM AUTHOR]