1. Effects of exercise and diet intervention on appetite-regulating hormones associated with miRNAs in obese children
- Author
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Dan Wang, Ming-Qiang Xiang, Honggang Yin, Junhao Huang, Min Hu, Jingwen Liao, Shen Wang, Fengpeng Xu, and Hailin Deng
- Subjects
050103 clinical psychology ,medicine.medical_specialty ,030309 nutrition & dietetics ,media_common.quotation_subject ,Appetite ,03 medical and health sciences ,Internal medicine ,Intervention (counseling) ,microRNA ,medicine ,Humans ,0501 psychology and cognitive sciences ,Obesity ,Child ,Exercise ,media_common ,0303 health sciences ,business.industry ,Leptin ,digestive, oral, and skin physiology ,05 social sciences ,Fasting ,medicine.disease ,Orexin ,MicroRNAs ,Psychiatry and Mental health ,Clinical Psychology ,Endocrinology ,Ghrelin ,business ,Hormone - Abstract
This study investigated the effects of exercise and diet intervention on appetite-regulating hormones and subjective appetite changes in obese children and examined expressions of specific key microRNAs (miRNA, miR). 16 obese children were included in a training program consisting of exercise and diet intervention for 6 weeks. Before and after the intervention, fasting blood was collected to determine appetite-regulating hormones (leptin, ghrelin, and orexin) and miRNA (miR-103a-3p and miR-200a-3p) levels; eating behavior of the children was reported using the Children Eating Behavior Questionnaire (CEBQ). The level of orexin was significantly decreased (P
- Published
- 2020
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