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Background and objective Supramandibular facial lymph nodes (SFLNs) are one of the unusual sites of lymph nodes metastases. This prospective study investigated the possible involvement of SFLNs in cases of head and neck carcinoma. Patients and methods SFLNS were identified and dissected from 30 neck dissections obtained from 30 patients (22 male individuals and eight female individuals) with squamous cell carcinoma (SCC) of the oral cavity without locoregional recurrence or distant metastases. Result Histopathological examination of the removed SFLN nodes proved positive for metastases in nine neck dissections, five cases of buccal mucosa SCC (41.7% of the cases) and four cases of alveolar margin SCC (44.4% of the cases). Conclusion SFLNs are a probable site of lymph node metastases in SCC of the alveolar margin and buccal mucosa. Careful dissection above the lower margin of the mandible can safely remove these nodes without significant injury to the marginal mandibular branch of the facial nerve. [ABSTRACT FROM AUTHOR]

Introduction Conservative surgery has become a well-established alternative to mastectomy in the treatment of breast cancer. However, in case of larger lesions or small-sized breasts, the removal of adequate volumes of breast tissue to achieve tumor-free margins and reducing the risk of local relapse may compromise the cosmetic outcome, causing unpleasant results. To address this issue, surgical techniques, the so-called oncoplastic techniques, have been introduced in recent years to optimize the efficacy of conservative surgery in terms of both local control and cosmetic results. Patients and methods A Clinical Interventional descriptive single arm randomized prospective study, conducted on twenty female patients presenting with operable breast cancer stages 1 and 2 located at the Upper or Central breast. Ages ranging 25 to 75 years to be treated using the “round block” technique. Results Cosmetic results were found to be excellent in three cases, good in eight cases, fair in five cases, and poor in two cases. In this study, the cosmetic results were unacceptable (fair and poor) in patients who underwent 25% resection or in whom the resected area was part of the lower portion of the breast. Conclusion These techniques are useful for performing breast-conserving surgery in the upper portion of the breast. However, if the excision volume is greater than 20% or excision of part of the lower portion of the breast is required, other procedures should be considered. This article discusses the indications, advantages, and limitations of the round block breast-conserving oncoplastic techniques and its results in terms of feasibility, maintaining breast esthetics, limitations, and early complications. [ABSTRACT FROM AUTHOR]

Purpose The aim of the study was to determine the feasibility and accuracy of sentinel lymph node biopsy (SLNB) in patients with advanced breast cancer after preoperative chemotherapy. Patients and methods A prospective study was conducted on 73 patients with advanced operable breast carcinoma previously treated with preoperative chemotherapy. Sentinel lymph node (SLN) mapping was performed at the time of surgery. Following surgery all patients received comprehensive postoperative radiotherapy at 50 Gy/5 weeks. Results Seventy-three patients with a median age of 52 years who had been previously treated with preoperative chemotherapy at Menofia University Hospital and National Cancer Institute (NCI) between May 2006 and May 2013 were selected for this study. The SLN detection rate was 79.5%. Thirty-three of 58 patients (56.9%) had successfully mapped positive SLNs. The false-negative rate was 22.4%. Conclusion This study confirms the feasibility of SLNB after preoperative chemotherapy in the case of advanced operable breast cancer. According to the detection rate and false-negative rate SLNB may predict metastatic disease in the axilla of patients with tumor response following preoperative chemotherapy. [ABSTRACT FROM AUTHOR]