1. CANCEROLITIC ACTION OF E. coli.
- Author
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Shahinyan, A., Garibyan, J., Pepoyan, A., and Karapetyan, O.
- Subjects
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PHOSPHOLIPIDS , *CELL communication , *CANCER patients , *ESCHERICHIA coli , *METHYLATION , *DNA - Abstract
The investigation of phospholipid composition of cellular walls and plasmatic membranes and the primary structure of DNA molecules of E. coli obtained from healthy and cancer-ill persons, and also the change of primary structure of DNA of model rumor cells of sarcoma 45, before and after its interaction with E. coli in vitro, reveals that: a) Cell walls and plasmatic membranes of E. coli obtained from cancer-ill persons must be more stable to poly ions, in particular to C++ ions, but at the same time on average must have considerably smaller stability, than the membranes of E. coli, obtained from the healthy people; b) The level of methylation of DNA in E. coli from cancer-ill persons is sharply suppressed; c) The bacterium of E. coli, obtained from the healthy people can act in a role of genome inductor, changing primary structure of rumors DNA via its demethylation. [ABSTRACT FROM AUTHOR]
- Published
- 2003