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The success of machine learning (ML) techniques in the formerly difficult areas of data analysis and pattern extraction has led to their widespread incorporation into various aspects of human life. This success is due in part to the increasing computational power of computers and in part to the improved ability of ML algorithms to process large amounts of data in various forms. Despite these improvements, certain issues, such as privacy, continue to hinder the development of this field. In this context, a privacy-preserving, distributed, and collaborative machine learning technique called federated learning (FL) has emerged. The core idea of this technique is that, unlike traditional machine learning, user data is not collected on a central server. Nevertheless, models are sent to clients to be trained locally, and then only the models themselves, without associated data, are sent back to the server to combine the different locally trained models into a single global model. In this respect, the aggregation algorithms play a crucial role in the federated learning process, as they are responsible for integrating the knowledge of the participating clients, by integrating the locally trained models to train a global one. To this end, this paper explores and investigates several federated learning aggregation strategies and algorithms. At the beginning, a brief summary of federated learning is given so that the context of an aggregation algorithm within a FL system can be understood. This is followed by an explanation of aggregation strategies and a discussion of current aggregation algorithms implementations, highlighting the unique value that each brings to the knowledge. Finally, limitations and possible future directions are described to help future researchers determine the best place to begin their own investigations.

Machine Learning (ML) and Deep Learning (DL) are derivatives of Artificial Intelligence (AI) that have already demonstrated their effectiveness in a variety of domains, including healthcare, where they are now routinely integrated into patients’ daily activities. On the other hand, data heterogeneity has long been a key obstacle in AI, ML and DL. Here, Multimodal Machine Learning (Multimodal ML) has emerged as a method that enables the training of complex ML and DL models that use heterogeneous data in their learning process. In addition, Multimodal ML enables the integration of multiple models in the search for a single, comprehensive solution to a complex problem. In this review, the technical aspects of Multimodal ML are discussed, including a definition of the technology and its technical underpinnings, especially data fusion. It also outlines the differences between this technology and others, such as Ensemble Learning, as well as the various workflows that can be followed in Multimodal ML. In addition, this article examines in depth the use of Multimodal ML in the detection and prediction of Cardiovascular Diseases, highlighting the results obtained so far and the possible starting points for improving its use in the aforementioned field. Finally, a number of the most common problems hindering the development of this technology and potential solutions that could be pursued in future studies are outlined.