1. Oncogenic Kinases in Cancer
- Author
-
Alexandros Zafiropoulos and Antonis Tsintarakis
- Subjects
Serine/threonine-specific protein kinase ,biology ,Chemistry ,p38 mitogen-activated protein kinases ,Mitogen-activated protein kinase ,biology.protein ,JAK-STAT signaling pathway ,AKT2 ,Polo-like kinase ,AKT3 ,Receptor tyrosine kinase ,Cell biology - Abstract
Oncogenesis involves the generation and transmission of signals that result in deregulation of cell proliferation, inhibition of apoptosis and morphological changes. Transmembrane or cytoplasmic tyrosine and serine/threonine kinases participate both directly and indirectly in cell transformation and tumorigenesis. Keywords: tyrosine kinases; receptor kinases; serine/threonine kinases; cell cycle; apoptosis
- Published
- 2017
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