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Your search keyword '"Arendrup, Maiken C"' showing total 7 results
Start Over Author "Arendrup, Maiken C" Journal emerging infectious diseases
7 results on '"Arendrup, Maiken C"'

1. In Vivo Selection of a Unique Tandem Repeat Mediated Azole Resistance Mechanism ([TR.sub.120]) in Aspergillus fumigatus cyp51A, Denmark

Author

Hare, Rasmus K., Gertsen, Jan B., Astvad, Karen M.T., Degn, Kristine B., Lokke, Anders, Stegger, Marc, Andersen, Paal S., Kristensen, Lise, and Arendrup, Maiken C.

Subjects
Research, Care and treatment, Complications and side effects, Usage, Drug resistance -- Research, Aspergillus -- Care and treatment -- Complications and side effects, Azoles -- Usage, Fungicides, Death, DNA sequencing, Antifungal agents, Genomics, Aspergillosis, Posaconazole, Steroids (Organic compounds), Genomes, Mycoses
Abstract

Azole antifungal drug resistance in Aspergillus fumigatus is a concern for patients with aspergillosis because of increased risk for disease and death (1). Two routes of acquiring azole resistance have [...]

Published
2019
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2. Frequency and evolution of azole resistance in Aspergillus fumigatus associated with treatment failure

Author

Howard, Susan J., Cerar, Dasa, Anderson, Michael J., Albarrag, Ahmed, Fisher, Matthew C., Pasqualotto, Alessandro C., Laverdiere, Michel, Arendrup, Maiken C., Perlin, David S., and Denning, David W.

Subjects
Care and treatment, Analysis, Natural history, Health aspects, Algorithm, Itraconazole -- Health aspects -- Analysis, Cross infection -- Care and treatment -- Health aspects -- Analysis, Chronic obstructive lung disease -- Care and treatment -- Health aspects -- Analysis, Evolutionary biology -- Health aspects -- Analysis, Methionine -- Health aspects -- Analysis, Drug resistance -- Care and treatment -- Health aspects -- Analysis, Hematopoietic stem cell transplantation -- Health aspects -- Analysis, Triazoles -- Health aspects -- Analysis, Amphotericin B -- Health aspects -- Analysis, Algorithms -- Health aspects -- Analysis, Mycoses -- Care and treatment -- Health aspects -- Analysis, Antiparasitic agents -- Health aspects -- Analysis, Gene mutation -- Health aspects -- Analysis, Endowments -- Health aspects -- Analysis, Codons -- Health aspects -- Analysis, Gene mutations -- Health aspects -- Analysis, Codon -- Health aspects -- Analysis, Lung diseases, Obstructive -- Care and treatment -- Health aspects -- Analysis, Hematopoietic stem cells -- Transplantation, Nosocomial infections -- Care and treatment -- Health aspects -- Analysis
Abstract

Invasive aspergillosis in immunosuppressed patients is difficult to diagnose, is problematic to treat, and results in a high mortality rate (1). Chronic and allergic pulmonary and sinus aspergillosis are increasingly [...]

Published
2009
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4. In Vivo Selection of a Unique Tandem Repeat Mediated Azole Resistance Mechanism (TR120) in Aspergillus fumigatus cyp51A, Denmark.

Author

Hare, Rasmus K., Gertsen, Jan B., Astvad, Karen M. T., Degn, Kristine B., Løkke, Anders, Stegger, Marc, Andersen, Paal S., Kristensen, Lise, and Arendrup, Maiken C.

Subjects
TANDEM repeats, ASPERGILLUS fumigatus, AZOLES
Abstract

We report a fatal aspergillosis case in which STRAf typing and whole-genome sequencing substantiated in vivo emergence of an azole-resistant Aspergillus fumigatus with a 120-bp tandem repeat in the promoter region of cyp51A. This event, previously restricted to the environment, challenges current understanding of azole resistance development in A. fumigatus. [ABSTRACT FROM AUTHOR]

Published
2019
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7. Azole Resistance of Aspergillus fumigatus in Immunocompromised Patients with Invasive Aspergillosis.

Author

van der Linden, Jan W. M., Arendrup, Maiken C., Melchers, Willem J. G., and Verweij, Paul E.

Subjects
*DRUG resistance in bacteria, *ASPERGILLUS fumigatus, *ANTIFUNGAL agents, *ASPERGILLOSIS, *ASPERGILLUS, *DRUG resistance in microorganisms, *HETEROCYCLIC compounds, *PUBLIC health surveillance, *PHARMACODYNAMICS
Abstract

A response from the authors to a letter to the editor about their article "Prospective Multicenter International Surveillance of Azole Resistance in Aspergillus Fumigatus," in a 2015 issue is presented.

Published
2016
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