1. Extensive Mammalian Ancestry of Pandemic (H1N1) 2009 Virus
- Author
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Natalia A. Ilyushina, Jeong-Ki Kim, Nicholas J. Negovetich, Young-Ki Choi, Victoria Lang, Nicolai V. Bovin, Heather L. Forrest, Min-Suk Song, Philippe Noriel Q. Pascua, Chul-Joong Kim, Robert G. Webster, and Richard J. Webby
- Subjects
Pandemic (H1N1) 2009 ,H1N1 ,hemagglutinin ,receptor specificity ,infectivity and transmission in avian species ,viruses ,Medicine ,Infectious and parasitic diseases ,RC109-216 - Abstract
We demonstrate that the novel pandemic influenza (H1N1) viruses have human virus–like receptor specificity and can no longer replicate in aquatic waterfowl, their historic natural reservoir. The biological properties of these viruses are consistent with those of their phylogenetic progenitors, indicating longstanding adaptation to mammals.
- Published
- 2010
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