1. [ACTH-dependent Cushing syndrome, a diagnostic challenge].
- Author
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Fuentes Tudanca S, Ortiz de Urbina PM, De Dios LM, Gallego Rodríguez S, Pérez Pelayo M, and Del Olmo García D
- Subjects
- ACTH Syndrome, Ectopic blood, ACTH Syndrome, Ectopic complications, Adrenocorticotropic Hormone analysis, Adult, Biomarkers, Tumor analysis, Bronchial Neoplasms chemistry, Bronchial Neoplasms diagnosis, Bronchial Neoplasms diagnostic imaging, Bronchial Neoplasms surgery, Bronchoscopy, Carcinoid Tumor chemistry, Carcinoid Tumor diagnosis, Carcinoid Tumor diagnostic imaging, Carcinoid Tumor surgery, False Negative Reactions, Female, Humans, Hypophysectomy, Pneumonectomy, Radiography, Unnecessary Procedures, ACTH Syndrome, Ectopic diagnosis, Bronchial Neoplasms metabolism, Carcinoid Tumor metabolism, Cushing Syndrome etiology, Diagnostic Errors, Pituitary ACTH Hypersecretion diagnosis
- Abstract
ACTH dependent Cushing syndrome accounts for approximately 80% of all Cushing syndrome. Distinguishing the pituitary origin from ectopic one is still a diagnosis problem in some cases, especially in bronchial carcinoids, because approximately 50% show cortisol suppresion after dexametasone and may be small and, therefore, difficult to detect in chest radiography. We present a case of a patient with ACTH dependent Cushing syndrome of difficult localization with usual diagnosis tests.
- Published
- 2009
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