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Abstract: The influence of site effects on landslide triggering during earthquakes has been inferred in several studies, but its evaluation is made difficult by the complexity of factors controlling the dynamic response of potentially unstable slopes and also by the lack of local ground motion instrumental observations. This work explores this problem and reports new findings based on an ongoing long term accelerometric monitoring conducted on a landslide-prone test area in the Apennine Mountains, Italy, where the presence of site effects enhancing seismic susceptibility of local slopes has been invoked on the basis of historic accounts of landsliding triggered at large epicentral distance. The recordings relative to low-to-moderate magnitude earthquakes showed significant amplifications affecting hillslope portions covered by thick (>5m) colluvia and pronounced amplification maxima oriented along the local maximum slope direction on a recent deep-seated landslide. While the amplifications seem most likely linked to high impedance contrast between surface materials and underlying substratum, the causes of directivity are less clear. The case of the monitored test site together with evidence of site response directivity identified on other hillslopes, suggest that the directivity phenomena can result from a combination of topographic, lithological and structural factors that act together to re-distribute shaking energy, focusing it on site-specific directions. Thus, it is difficult to single out the critical factors controlling such phenomena and no general criterion for the identification of sites affected by directivity is proposed here. Nevertheless, the presence and orientation of site response directivity can be revealed through reconnaissance techniques by using recordings of seismic weak motion and/or ambient microtremors, and calculating azimuthal variation of shaking energy and horizontal-to-vertical ground motion spectral ratios. A comparison with the recordings obtained during the recent MW =6.3 earthquake that hit the Abruzzo region in April 2009 demonstrated that analysis relying on data from low energy events can furnish valid indications for slope behaviour also under stronger shaking, provided the data are well differentiated in terms of distance, azimuth and source characteristics. Furthermore, the comparative analysis of the Abruzzo earthquake recordings at a landslide and reference sites showed that directivity properties of strong shaking had been correctly anticipated using earlier weak motion observations. However, under the complex slope conditions the identification of resonance frequencies from horizontal-to-vertical spectral ratios estimated from weak-motion accelerometric recordings does not seem reliable, and better results have been obtained by velocimetric microtremor recordings. [Copyright &y& Elsevier]